Antibacterial activity of turmeric oil: A byproduct from curcumin manufacture
Antibacterial activity of turmeric oil: A byproduct from curcumin manufacture
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DOI：
10.1021/jf990308d
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发表时间：
1999-10-01
影响因子：
6.1
通讯作者：
Sakariah, KK
中科院分区：
文献类型：
--
作者：
Negi, PS;Jayaprakasha, GK;Sakariah, KK
姜黄素是姜黄的黄色色素，工业上由姜黄油树脂生产。从油树脂中分离出姜黄素后的母液含油量约为40%。用正己烷在60℃下从母液中提取油，用硅胶柱层析法将正己烷萃取物分离成三段。用淋板法对蜡样芽孢杆菌、凝固芽孢杆菌、枯草芽孢杆菌、金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌进行抑菌活性测试。用5%乙酸乙酯在己烷中洗脱的组分ⅱ活性最强。采用气相色谱法和气相色谱-质谱法对姜黄油、ⅰ、ⅱ组分进行分析。在这些馏分中发现了ar-黄酮，黄酮和屈酮以及其他含氧化合物的主要化合物。
Curcumin, the yellow color pigment of turmeric, is produced industrially from turmeric oleoresin. The mother liquor after isolation of curcumin from oleoresin contains approximately 40% oil. The oil was extracted from the mother liquor using hexane at 60 degrees C, and the hexane extract was separated into three fractions using silica gel column chromatography. These fractions were tested for antibacterial activity by pour plate method against Bacillus cereus, Bacillus coagulans, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. Fraction II eluted with 5% ethyl acetate in hexane was found to be most active fraction. The turmeric oil, fraction I, and fraction II were analyzed by GC and GC-MS. ar-Turmerone, turmerone, and curlone were found to be the major compounds present in these fractions along with other oxygenated compounds.