Anti TB drug resistance in Tanga, Tanzania: a cross sectional facility base prevalence among pulmonary TB patients
Anti TB drug resistance in Tanga, Tanzania: a cross sectional facility base prevalence among pulmonary TB patients
复制标题
DOI：
10.1016/j.apjtm.2015.10.014
复制
发表时间：
2015-11-01
影响因子：
3.1
通讯作者：
Koenig, Brigitte
中科院分区：
文献类型：
--
作者：
Hoza, Ha Abubakar S.;Mfinanga, Sayoki G. M.;Koenig, Brigitte
目的：了解坦桑尼亚坦加地区基层医院耐药结核病（TB）的患病率及其危险因素。研究方法：在2012年11月至2013年1月进行的一项前瞻性研究期间，从372名（312名新患者和60名既往治疗患者）自我转诊至4家结核病诊所的结核病疑似患者中收集了总计79株结核分枝杆菌（MTB）分离株。在德国莱比锡大学医院医学微生物学和传染病流行病学研究所对分离株进行培养和药敏试验。有关患者特征的数据是从向给予口头知情同意的患者进行的结构化问卷中获得的。采用未校正的双变量logistic回归分析评估耐药结核病的危险因素。显著性水平确定为P
Objective: To determine the prevalence and risk factors associated with drug resistance tuberculosis (TB) at facility-base level in Tanga, Tanzania. Methods: A total of 79 Mycobacterium tuberculosis (MTB) isolates included in the study were collected from among 372 (312 new and 60 previously treated) TB suspects self referred to four TB clinics during a prospective study conducted from November 2012 to January 2013. Culture and drug susceptibility test of the isolates was performed at the institute of medical microbiology and epidemiology of infectious diseases, University hospital, Leipzig, Germany. Data on the patient's characteristics were obtained from structured questionnaire administered to the patients who gave informed verbal consent. Unadjusted bivariate logistic regression analysis was performed to assess the risk factors for drug resistant-TB. The significance level was determined at P