Low- and high-carbohydrate weight-loss diets have similar effects on mood but not cognitive performance
Low- and high-carbohydrate weight-loss diets have similar effects on mood but not cognitive performance
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DOI：
10.1093/ajcn/86.3.580
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发表时间：
2007-09-01
影响因子：
7.1
通讯作者：
Clifton, Peter M.
中科院分区：
文献类型：
--
作者：
Halyburton, Angela K.;Brinkworth, Grant D.;Clifton, Peter M.
背景资料：低碳水化合物饮食通常用于促进减肥，但其对心理功能的影响在很大程度上是未知的。目的：我们比较了低碳水化合物，高脂肪（LCHF）饮食与传统的高碳水化合物，低脂肪（HCLF）饮食对情绪和认知功能的影响。设计：93名超重或肥胖参与者[x +/- SEM年龄：50.2 +/- 0.8岁;体重指数（kg/m2）：33.6 +/- 0.4]被随机分配到能量限制（约6-7 MJ，30%赤字），计划等热量LCHF饮食或HCLF饮食8周。在基线和每两周使用情绪状态、贝克抑郁量表和Spielberger状态焦虑量表测量体重和心理健康。在基线和第8周评估认知功能（工作记忆和处理速度）。结果：LCHF饮食导致的体重减轻显著大于HCLF饮食（分别为7.8 +/- 0.4和6.4 +/- 0.4 kg; P = 0.04）。两组患者的心理健康状况均有所改善（时间P < 0.01），最大的改善发生在治疗的前2周，但两组之间无显著差异。有没有显着的组间差异，工作记忆（P = 0.68），但有一个显着的时间X饮食相互作用的处理速度（P = 0.04），使这一措施改善LCHF比在HCLF饮食group.Conclusions：这两种饮食模式显着降低体重，并与改善情绪。有一些证据表明，LCHF饮食在处理速度方面对认知功能有较小的改善，但需要进一步的研究来确定这一发现的可复制性。
Background: Low-carbohydrate diets are often used to promote weight loss, but their effects on psychological function are largely unknown.Objective: We compared the effects of a low-carbohydrate, high-fat (LCHF) diet with a conventional high-carbohydrate, low-fat (HCLF) diet on mood and cognitive function.Design: Ninety-three overweight or obese participants [x +/- SEM age: 50.2 +/- 0.8 y; body mass index (in kg/m(2)): 33.6 +/- 0.4] were randomly assigned to an energy-restricted (approximate to 6-7 MJ, 30% deficit), planned isocaloric LCHF diet or an HCLF diet for 8 wk. Body weight and psychological well-being were measured by using the Profile of Mood States, Beck Depression Inventory, and Spielberger State Anxiety Inventory instruments at baseline and fortnightly. Cognitive functioning (working memory and speed of processing) was assessed at baseline and week 8.Results: The LCHF diet resulted in significantly greater weight loss than did the HCLF diet (7.8 +/- 0.4 and 6.4 +/- 0.4 kg, respectively; P = 0.04). Both groups showed improvements in psychological well-being (P < 0.01 for time), with the greatest effect occurring during the first 2 wk, but there was no significant difference between groups. There were no significant between-group differences in working memory (P = 0.68), but there was a significant time X diet interaction for speed of processing (P = 0.04), so that this measure improved less in the LCHF than in the HCLF diet group.Conclusions: Both dietary patterns significantly reduced body weight and were associated with improvements in mood. There was some evidence for a smaller improvement in cognitive functioning with the LCHF diet with respect to speed of processing, but further studies are required to determine the replicability of this finding.