Exercise and dementia prevention
Exercise and dementia prevention
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DOI：
10.1136/practneurol-2019-002335
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发表时间：
2020-05-01
影响因子：
2.8
通讯作者：
Lawler, Katherine
中科院分区：
文献类型：
--
作者：
Alty, Jane;Farrow, Maree;Lawler, Katherine
衰老、遗传、医疗和生活方式因素会增加患阿尔茨海默病和其他痴呆症的风险。大约三分之一的痴呆症病例可归因于可改变的风险因素，如缺乏运动、吸烟和高血压。随着患病率的上升和神经保护药物的缺乏，人们重新关注整个生命周期的痴呆症预防策略。神经科医生遇到许多有痴呆症风险因素的人，经常被问到改变生活方式是否有帮助。运动已成为积极影响认知的关键干预措施，包括降低与年龄相关的认知能力下降和痴呆症的风险。本文重点介绍了目前的证据表明，缺乏身体活动是一种可改变的痴呆症风险因素，旨在支持神经科医生在讨论降低风险时。
Ageing, genetic, medical and lifestyle factors contribute to the risk of Alzheimer's disease and other dementias. Around a third of dementia cases are attributable to modifiable risk factors such as physical inactivity, smoking and hypertension. With the rising prevalence and lack of neuroprotective drugs, there is renewed focus on dementia prevention strategies across the lifespan. Neurologists encounter many people with risk factors for dementia and are frequently asked whether lifestyle changes may help. Exercise has emerged as a key intervention for influencing cognition positively, including reducing the risk of age-related cognitive decline and dementia. This article focuses on the current evidence for physical inactivity as a modifiable dementia risk factor and aims to support neurologists when discussing risk reduction.