High-Resolution Versus High-Sensitivity SPECT Imaging With Geometric Blurring Compensation for Various Parallel-Hole Collimation Geometries
High-Resolution Versus High-Sensitivity SPECT Imaging With Geometric Blurring Compensation for Various Parallel-Hole Collimation Geometries
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DOI：
10.1109/titb.2010.2050145
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发表时间：
2010-07-01
影响因子：
--
通讯作者：
Zeng, Gengsheng L.
中科院分区：
文献类型：
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作者：
Zhang, Bin;Zeng, Gengsheng L.
最近的研究表明，提高分辨率的贸易效率可能是一个很好的选择，为小病变检测，但利用准直器与高效率可能更有利于心脏单光子发射计算机断层扫描（SPECT）。本文研究了几何模糊补偿的高分辨率（HR）和高灵敏度（HS）SPECT成像与各种平行孔准直器的降噪和分辨率恢复方面的权衡。五种类型的准直器进行了研究，并与一般的通用准直器使用计算机模拟进行了比较。结果表明，使用带有模糊补偿的大准直器孔，可以在空间分辨率不变的情况下获得噪音较小的SPECT图像。在计算机模拟中找到的最佳准直器孔是具有在6.3 °至9.4 °范围内的孔接收角的孔。两个心脏插入体模的体模实验表明，使用HS准直器获得的图像的分辨率可以通过模糊补偿成功地恢复，并且与使用HR准直器获得的图像相比，图像的噪声更小。
Recent studies have shown that trading efficiency for improved resolution may be a good choice for small lesion detection, but utilizing collimator with high efficiency may be more favorable for cardiac single photon emission computed tomography (SPECT). This paper investigates the tradeoffs of geometric-blurring compensation for high-resolution (HR) and high-sensitivity (HS) SPECT imaging with various parallel-hole collimators in terms of noise reduction and resolution recovery. Five types of collimators were investigated and compared with a general all purpose collimator using computer simulations. It is shown that less noisy SPECT images can be achieved with unchanged spatial resolution using large collimator holes with blurring compensation. The optimal collimator hole found in the computer simulation is the one with a hole acceptance angle in the range from 6.3 to 9.4. Phantom experiments with two cardiac-insert phantoms show that the resolution of the image obtained using the HS collimator can be successfully recovered by blurring compensation, and the image is less noisy compared to the one obtained using the HR collimator.