Prospective Validation of Objective Prognostic Score for Advanced Cancer Inpatients in South Korea: A Multicenter Study.

Prospective Validation of Objective Prognostic Score for Advanced Cancer Inpatients in South Korea: A Multicenter Study.
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韩国晚期癌症住院患者客观预后评分的前瞻性验证:一项多中心研究。

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发表时间:
2017
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通讯作者:
P. Uk
P. Uk
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作者:
YoonSeok Joon;SuhSang;L. Joo;ParkJeanno;HwangSunwook;LeeSanghee Shiny;AhnHong Yup;KohSu;P. Uk

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摘要背景:目的预后评分(OPS)是韩国发展起来的一种简便易行的预测工具。它已经在韩国的一个中心进行了追溯验证。目的:我们旨在通过一项多中心研究对韩国晚期癌症住院患者的OPS进行前瞻性验证。设计:这是一项前瞻性队列研究。地点/对象:从2013年5月至2015年3月,我们在韩国的5个姑息治疗病房招募了243名晚期癌症患者。韩国姑息医学研究网络的七名成员是姑息治疗的专家,他们领导了这项研究。测量:在登记时收集临床变量(呼吸困难/厌食/表现状态)和实验室变量(总白细胞计数/血清总胆红素/血清肌酐/乳酸脱氢酶)。存活时间以从入院到入院期间死亡天数计算。结果:共217例患者进入最终分析(可行性:89.3%)。苏……
Abstract Background: Objective Prognostic Score (OPS) was developed as an easy and simple prognosticating tool in South Korea. It has been validated retrospectively in a single center in South Korea. Objective: We aimed to validate the OPS prospectively for advanced cancer inpatients in South Korea using a multicenter study. Design: This was a prospective cohort study. Setting/Subjects: We enrolled 243 advanced cancer patients admitted in five palliative care units in South Korea from May 2013 till March 2015. Seven members of the Korean Palliative Medicine Research Network who are experts of palliative care led the study. Measurements: Clinical variables (dyspnea/anorexia/performance status) and laboratory variables (total leukocyte counts/serum total bilirubin/serum creatinine/lactate dehydrogenase) were collected at the enrollment. Survival time was calculated as days from enrollment to death during admission. Results: A total of 217 patients were included in the final analysis (feasibility: 89.3%). Su...