Simple highly modular acyclic amine-catalyzed direct enantioselective addition of ketones to nitro-olefins.
Simple highly modular acyclic amine-catalyzed direct enantioselective addition of ketones to nitro-olefins.
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DOI：
10.1039/b514783m
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发表时间：
2006-01
影响因子：
4.9
通讯作者：
Yongmei Xu;A. Córdova
中科院分区：
文献类型：
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作者：
Yongmei Xu;A. Córdova
简单、高度模块化的伯氨基酸衍生物催化酮与硝基烯烃的直接对映选择性加成，具有高度立体控制，并以高达>38 1 dr和高达99%ee的高产率提供相应的羟醛产物。
Simple, highly modular primary amino acid derivatives catalyze the direct enantioselective addition of ketones to nitro-olefins with high stereocontrol and furnish the corresponding aldol products in high yield with up to >38 1 dr and up to 99% ee.