High Prevalence of Sexual Dysfunction in a Vulvovaginal Specialty Clinic.
High Prevalence of Sexual Dysfunction in a Vulvovaginal Specialty Clinic.
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DOI：
10.1097/lgt.0000000000000085
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发表时间：
2016-01
影响因子：
3.7
通讯作者：
Mitchell CM
中科院分区：
文献类型：
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作者：
Gordon D;Gardella C;Eschenbach D;Mitchell CM
我们的研究评估了外阴阴道专科门诊人群中性功能障碍的存在和预测因素。到外阴阴道专科诊所就诊的妇女有资格参加研究。参与者完成了一份调查问卷，包括评估性功能障碍的女性性功能指数（FSFI）和患者健康问卷(PHQ)-9抑郁筛查，并进行了标准化的体检，收集阴道拭子进行湿载和培养。Logistic回归评估性功能障碍与临床诊断的关系。我们招募了161名女性，年龄18-80岁（中位数= 36），表现为外阴阴道不适。中位症状持续时间为24个月；131名女性（81%）报告了慢性症状（≥12个月）。根据PHQ-9, 28名（17%）女性符合抑郁标准。在评估前一个月，86名（53%）女性出现性功能障碍。女性主要诊断为阴道炎（n = 46, 29%）、前庭痛/外阴炎（n = 70, 43%）、扁平苔藓或硬化苔藓（n = 24, 15%）。在控制年龄因素后，性功能障碍与慢性症状（IRR 0.86, 95% CI 0.50-1.48）、抑郁（IRR 1.24, 95% CI 0.59, 2.58）或三种主要诊断中的任何一种（IRR 1.16, 95% CI 0.47, 2.88）无关。在外阴阴道炎转诊诊所，超过一半的女性存在性功能障碍，这一比例是一般人群的两倍多。
Our study evaluated the presence and predictors of sexual dysfunction in a vulvovaginal specialty clinic population. Women who presented to a vulvovaginal specialty clinic were eligible to enroll. Participants completed a questionnaire, including Female Sexual Function Index (FSFI) to assess sexual dysfunction and Patient Health Questionnaire (PHQ)-9 depression screen, and underwent a standardized physical exam, with vaginal swabs collected for wet mount and culture. Logistic regression assessed the relationship between sexual dysfunction and clinical diagnosis. We enrolled 161 women, aged 18–80 years (median = 36), presenting with vulvovaginal complaints. Median symptom duration was 24 months; 131 women (81%) reported chronic symptoms (≥12 months). By PHQ-9, 28 (17%) women met depression criteria. In the month prior to assessment, 86 (53%) women experienced sexual dysfunction. Women were primarily diagnosed with vaginitis (n = 46, 29%), vestibulodynia/vulvitis (n = 70; 43%), lichen planus or lichen sclerosus (n = 24; 15%). Controlling for age, sexual dysfunction did not correlate with chronic symptoms (IRR 0.86, 95% CI 0.50–1.48), depression (IRR 1.24; 95% CI 0.59, 2.58), or presence of any of the three main diagnoses (IRR 1.16, 95% CI 0.47, 2.88). Sexual dysfunction is present in over half of women presenting to a vulvovaginitis referral clinic, more than twice the rate in the wider population.