Nephrotoxic serum nephritis in chickens.
Nephrotoxic serum nephritis in chickens.
复制标题
鸡肾毒性血清肾炎。
DOI：
10.1080/03079458608436264
复制
发表时间：
1986
期刊：
影响因子：
--
通讯作者：
M. Sternberg
中科院分区：
文献类型：
--
作者：
M. Chandra;V. Marius;M. Michele;G. Bennejean;J. Lamandé;M. Sternberg
研究了鸡实验性肾毒性血清肾炎的生化和组织病理学变化。免疫荧光研究显示，在疾病的异源期和自体期，IgG 沿着肾小球基底膜线性沉积，分别具有单特异性抗兔 IgG 和单特异性抗鸡 IgG。总体组织病理学表现为增生性肾小球肾炎。在肾小球基底膜上没有 IgG 沉积的鸡中观察到同等甚至更严重的增殖性病变。超微结构显示系膜增生。肾小球基底膜出现增厚，但前体细胞正常。
Biochemical and histopathological changes in experimental nephrotoxic serum nephritis in chickens were studied. Immunofluorescence studies revealed linear deposits of IgG along the glomerular basement membrane with monospecific anti-rabbit IgG and monospecific anti-chicken IgG during heterologous and autologous phases of disease, respectively. The overall histopathological picture was of proliferative glomerulonephritis. Proliferative lesions of an equal or even greater severity were observed in chickens without IgG deposits on the glomerular basement membrane. Ultrastructurally, mesangium revealed hyperplasia. Glomerular basement membrane appeared thickened but prodocytes were normal.
影响因子：
15.9
作者：
HOLDSWORTH, SR;NEALE, TJ;WILSON, CB
通讯作者：
WILSON, CB
影响因子：
15.9
作者：
BOLTON, WK;TUCKER, FL;STURGILL, BC
通讯作者：
STURGILL, BC