Solubility of α-Tocopheryl Succinate in Supercritical Carbon Dioxide Using Offline HPLC-MS/MS Analysis.
Solubility of α-Tocopheryl Succinate in Supercritical Carbon Dioxide Using Offline HPLC-MS/MS Analysis.
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使用离线 HPLC-MS/MS 分析α-生育酚琥珀酸酯在超临界二氧化碳中的溶解度。
DOI：
10.1021/je700095q
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发表时间：
2007
影响因子：
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通讯作者：
Hybertson,BrooksM
中科院分区：
文献类型：
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作者：
Hybertson,BrooksM
测定了维生素E相关化合物α-生育酚琥珀酸酯在超临界二氧化碳中的溶解度，压力范围为15.0~30.0Mpa，温度为(40~50)°C，使用简单的微型取样器，以100.5μ的L样品回路去除等分并收集它们在乙醇中进行离线分析。采集的样品中的α-生育酚琥珀酸酯浓度采用高效液相色谱-串联质谱仪进行分析。α-生育酚琥珀酸酯在超临界二氧化碳中的溶解度范围为0.28×10-5(15.0 Mpa和50°C时)到2.56×10-5(30.0 Mpa和50°C时)。
The solubility of the vitamin E-related compound α-tocopheryl succinate in supercritical carbon dioxide was measured at pressures ranging from (15.0 to 30.0) MPa and temperatures of (40 and 50) °C using a simple microsampling type apparatus with a 100.5 μL sample loop to remove aliquots and collect them in ethanol for off line analysis. α-Tocopheryl succinate concentrations in the collected samples were measured using HPLC-MS/MS analysis. The solubility of α-tocopheryl succinate in supercritical carbon dioxide ranged from mole fractions of 0.28 × 10-5at 15.0 MPa and 50 °C to 2.56 × 10-5at 30.0 MPa and 50 °C.