Time-resolved 3-dimensional velocity mapping in the thoracic aorta - Visualization of 3-directional blood flow patterns in healthy volunteers and patients
Time-resolved 3-dimensional velocity mapping in the thoracic aorta - Visualization of 3-directional blood flow patterns in healthy volunteers and patients
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DOI：
10.1097/00004728-200407000-00005
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发表时间：
2004-07-01
影响因子：
1.3
通讯作者：
Herfkens, RJ
中科院分区：
文献类型：
--
作者：
Markl, M;Draney, MT;Herfkens, RJ
目的：分析正常受试者和有主动脉病理结果的患者的胸主动脉血流。使用各种可视化工具来分析整个胸主动脉的单个 3 分量速度体积采集内的血流模式方法：采用时间分辨、3 维相衬磁共振成像 (3D CINE PC MRI) 来获得整个胸主塔的完整空间和时间覆盖，并结合空间记录的 3 向脉动血流速度。三维可视化工具，包括重新格式化为任意二维剖切面的时间分辨速度矢量场、3D 流线和时间分辨 3D 粒子轨迹，被应用于一项有 10 名正常志愿者参与的研究中。 4 名患者的检查结果与志愿者扫描的扫描处方相似，以说明与胸主动脉常见病理结果相关的血流特征。结果：先前报告的胸主动脉血流模式，包括右旋螺旋流出、收缩后期逆行血流和加速通过主动脉瓣平面，在所有志愿者中均可见。临床病例说明了胸主动脉疾病对空间和时间血流模式的影响，包括升主动脉瘤、主动脉瓣反流和主动脉夹层。结论：时间分辨 3D 速度图已成功应用于 10 名健康志愿者和 4 名有主动脉病理结果记录的患者的研究中，并已被证明是分析和可视化整个正常特征以及病理血流特征的可靠工具。胸主动脉。
Objective: An analysis of thoracic aortic blood flow in normal subjects and patients with aortic pathologic findings is presented. Various visualization tools were used to analyze blood flow patterns within a single 3-component velocity volumetric acquisition of the entire thoracic aortaMethods: Time-resolved, 3-dimensional phase-contrast magnetic resonance imaging (3D CINE PC MRI) was employed to obtain complete spatial and temporal coverage of the entire thoracic aorta combined with spatially registered 3-directional pulsatile blood flow velocities. Three-dimensional visualization tools, including time-resolved velocity vector fields reformatted to arbitrary 2-dimensional cut planes, 3D streamlines, and time-resolved 3D particle traces, were applied in a study with 10 normal volunteers. Results from 4 patient examinations with similar scan prescriptions to those of the volunteer scans are presented to illustrate flow features associated with common pathologic findings in the thoracic aorta.Results: Previously reported blood flow patterns in the thoracic aorta, including right-handed helical outflow, late systolic retrograde flow, and accelerated passage through the aortic valve plane, were visualized in all volunteers. The effects of thoracic aortic disease on spatial and temporal blood flow patterns are illustrated in clinical cases, including ascending aortic aneurysms, aortic regurgitation, and aortic dissection.Conclusion: Time-resolved 3D velocity mapping was successfully applied in a study of 10 healthy volunteers and 4 patients with documented aortic pathologic findings and has proven to be a reliable tool for analysis and visualization of normal characteristic as well as pathologic flow features within the entire thoracic aorta.