Differences in the cargos and functions of exosomes derived from six cardiac cell types: a systematic review
Differences in the cargos and functions of exosomes derived from six cardiac cell types: a systematic review
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DOI：
10.1186/s13287-019-1297-7
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发表时间：
2019
影响因子：
7.5
通讯作者：
Huang Rong-chong
中科院分区：
文献类型：
--
作者：
Xu Ming-yue;Ye Zhi-shuai;Song Xian-tao;Huang Rong-chong
Exosomes are bilayer membrane vesicles with cargos that contain a variety of surface proteins, markers, lipids, nucleic acids, and noncoding RNAs. Exosomes from different cardiac cells participate in the processes of cell migration, proliferation, apoptosis, hypertrophy, and regeneration, as well as angiogenesis and enhanced cardiac function, which accelerate cardiac repair. In this article, we mainly focused on the exosomes from six main types of cardiac cells, i.e., fibroblasts, cardiomyocytes, endothelial cells, cardiac progenitor cells, adipocytes, and cardiac telocytes. This may be the first article to describe the commonalities and differences in regard to the function and underlying mechanisms of exosomes among six cardiac cell types in cardiovascular disease.
