Simultaneous determination of multiclass illegal dyes with different acidic–basic properties in foodstuffs by LC-MS/MS via polarity switching mode
Simultaneous determination of multiclass illegal dyes with different acidic–basic properties in foodstuffs by LC-MS/MS via polarity switching mode
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DOI：
10.1016/j.foodchem.2019.125745
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发表时间：
2019
期刊：
影响因子：
8.8
通讯作者：
李春远
中科院分区：
文献类型：
--
作者：
戚平;毛新武;李春远
Simultaneous determination of multiclass illegal dyes possessing different chemical properties is difficult. By using LC-MS/MS via negative/positive ion switching mode, an efficient and fast multi-residual method for simultaneous determination of multiclass 52 illegal dyes with different acidic–basic properties in foodstuffs was developed and validated during one single run, including 23 fat-soluble neutral azo dyes, 8 acidic sulfonated azo dyes, 12 triphenylmethane basic dyes, three basic indole dyes, three xanthene dyes, one quinoline dye, and two anthraquinones dyes. The illegal dyes were extracted with methanol-acetonitrile and further purified with d-SPE procedure to reduce interference. Sample dilution with 100-fold was used for the elimination of matrix effects of the quantitation of LC-MS/MS analysis. Validation data showed the good recoveries in the range of 71.2–111.2%, with relative standard deviations less than 20%, suggesting the developed method is suitable for the identification and quantitation of multiclass illegal dyes at trace levels in foods.
