Phytic acid doped poly(3,4-ethylenedioxythiophene) modified with copper nanoparticles for enzymeless amperometric sensing of glucose
Phytic acid doped poly(3,4-ethylenedioxythiophene) modified with copper nanoparticles for enzymeless amperometric sensing of glucose
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DOI：
10.1007/s00604-019-3988-2
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发表时间：
2019-12
影响因子：
5.7
通讯作者：
Lili Yang;Hao Wang;Haitao Lü;N. Hui
中科院分区：
文献类型：
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作者：
Lili Yang;Hao Wang;Haitao Lü;N. Hui
将植酸(PA)掺杂聚(3，4-乙二氧基噻吩基)(PEDOT)和铜纳米颗粒(CuNPs)修饰的纳米复合材料放置在玻碳电极上，应用于无酶葡萄糖传感器。起伏的PEDOT/PA复合材料具有良好的导电性和较大的比表面积，适合作为均匀生长CuNPs的衬底。修饰电极在0.55 V(vs.Ag/AgCl)附近的电位下对葡萄糖在氢氧化钠溶液中的直接氧化表现出显著的催化活性(这是该传感器的主要局限性)。优值系数包括：(A)分析范围宽(5~403μM)；(B)高灵敏度(79.27μA·μM−1·cm−2)；(C)低检测下限(0.28μM，信噪比为3)；(D)快速响应(<；4)S。将CuNPs/PEDOT/PA修饰电极应用于高性能的无酶葡萄糖传感器。
A nanocomposite consisting of phytic acid (PA) that was doped with poly(3,4-ethylenedioxy-thiophene) (PEDOT) and modified with copper nanoparticles (CuNPs) was placed on a glassy carbon electrode and then applied in an enzymeless glucose sensor. The undulating PEDOT/PA composite has good conductivity and a large surface area, which was suitable as substrate for the uniform growth of CuNPs. The modified electrode typically operated at a potential near 0.55 V (vs. Ag/AgCl) demonstrated remarkable catalytic activity towards direct oxidation of glucose in NaOH solution (the major limitation of this sensor). Figures of merit include (a) a wide analytical range (5 to 403 μM); (b) high sensitivity (79.27 μA·μM−1·cm−2), (c) a low detection limit (0.28 μM at a signal to noise ratio of 3), and (d) fast response (< 4 s).Graphical abstractA nanocomposite of phytic acid (PA) doped poly(3,4-ethylenedioxy-thiophene) (PEDOT) modified with copper nanoparticles (CuNPs) onto a glassy carbon electrode was prepared by electrochemical strategy. The CuNPs/PEDOT/PA-modified electrodes were applied in enzymeless glucose sensors with high performance.