Observing middle and inner ear mechanics with novel intracochlear pressure sensors
Observing middle and inner ear mechanics with novel intracochlear pressure sensors
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DOI：
10.1121/1.423083
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发表时间：
1998-06-01
影响因子：
2.4
通讯作者：
Olson, ES
中科院分区：
文献类型：
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作者：
Olson, ES
在沙鼠耳蜗基部体内测量耳蜗内压力。测量是在前庭阶和鼓室的各种频率上同时进行的。压力是在前庭阶中紧邻镫骨处以及间隔数十微米的多个位置处测量的，其中包括鼓阶中距基底膜几微米内的位置。基本结果得出两个结论。首先，鼓阶压力的空间变化表明压力由两种模式组成，可以用快波和慢波来识别。其次，在 2 至 46 kHz 之间的频率（测量的频率上限），镫骨附近的前庭阶压力相对于耳道中的压力有大约 30 dB 的增益，并且相位随频率线性下降。因此，在这些频率上，中耳及其在耳蜗中的终端作为与频率无关的传输线运行。进一步分析数据的子集，以得出基底膜的速度、柯蒂复合体器官（定义为包括盖层膜和基底膜）的压力差以及柯蒂复合体器官的比声阻抗。发现阻抗可以根据频率进行调整。 (C) 1998 年美国声学学会。
Intracochlear pressure was measured in vivo in the base of the gerbil cochlea. The measurements were made over a wide range of frequencies simultaneously in scalae vestibuli and tympani. Pressure was measured just adjacent to the stapes in scala vestibuli and at a number of positions spaced by tens of micrometers, including a position within several micrometers of the basilar membrane, in scala tympani. Two findings emerged from the basic results. First, the spatial variation in scala tympani pressure indicated that the pressure is composed of two modes, which can be identified with fast and slow waves. Second, at frequencies between 2 and 46 kHz (the upper frequency limit of the measurements) the scala vestibuli pressure adjacent to the stapes had a gain of approximately 30 dB with respect to the pressure in the ear canal, and a phase which decreased linearly with frequency. Thus, over these frequencies the middle ear and its termination in the cochlea operate as a frequency independent transmission line. A subset of the data was analyzed further to derive the velocity of the basilar membrane, the pressure difference across the organ of Corti complex (defined to include the tectorial and basilar membranes) and the specific acoustic impedance of the organ of Corti complex. The impedance was found to be tuned in frequency. (C) 1998 Acoustical Society of America.