Association between gestational diabetes and perinatal depressive symptoms: evidence from a Greek cohort study
Association between gestational diabetes and perinatal depressive symptoms: evidence from a Greek cohort study
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DOI：
10.1017/s1463423617000317
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发表时间：
2017-09-01
影响因子：
1.6
通讯作者：
Zervas, Iannis M.
中科院分区：
文献类型：
--
作者：
Varela, Pinelopi;Spyropoulou, Areti C.;Zervas, Iannis M.
目的：本研究的目的是评估希腊孕妇中妊娠期糖尿病(GDM)与产前和产后抑郁症状的关系。背景：早期的研究支持抑郁和糖尿病之间的关系，但只有少数研究检查了妊娠期糖尿病和围产期抑郁症状之间的关系。方法：共有117名妊娠晚期妇女参与了这项研究。人口统计和产科历史数据是在妇女怀孕的最后三个月期间记录的。在两个时间点：妊娠晚期和产后第一周，用经过验证的希腊版爱丁堡产后抑郁量表(EPDS)评估抑郁症状。结果：妊娠期糖尿病患病率为14.5%。在产前评估和产后评估中，12%的样本可能被诊断为抑郁症，15.1%的样本被诊断为抑郁症。在产后第一周，患有妊娠期糖尿病的妇女产后(但没有产前)的EPDS得分显著高于非妊娠期糖尿病组。总而言之，妊娠期糖尿病似乎与产后第一周的抑郁症状有关。讨论了临床意义和对未来研究的建议，强调密切监测患有妊娠期糖尿病的妇女的重要性，这些妇女似乎更容易在产后时期出现抑郁症状。
Aim: The aim of the present study was to assess the association of gestational diabetes mellitus (GDM) with prenatal and postnatal depressive symptoms in a sample of pregnant women in Greece. Background: Earlier research supports a relationship between depression and diabetes, but only a few studies have examined the relationship between GDM and perinatal depressive symptomatology. Methods: A total of 117 women in their third trimester of pregnancy participated in the study. Demographic and obstetric history data were recorded during women's third trimester of pregnancy. Depressive symptoms were assessed with the validated Greek version of the Edinburg Postnatal Depression Scale (EPDS) at two time points: on the third trimester of pregnancy and on the first week postpartum. Findings: Prevalence of GDM was 14.5%. Probable diagnosis of depression occurred for 12% of the sample during the antenatal assessment and 15.1% in the postpartum assessment. In the first week postpartum, women with GDM had significantly higher postpartum (but no antenatal) EPDS scores compared with the non-GDM cohort. In conclusion, GDM appears to be associated with depressive symptoms in the first week postpartum. Clinical implications and recommendations for future research are discussed, emphasizing the importance of closely monitoring women with GDM who seem more vulnerable to developing depressive symptomatology during the postnatal period.