Vitamin E and neurological function: abetalipoproteinaemia and other disorders of fat absorption.
Vitamin E and neurological function: abetalipoproteinaemia and other disorders of fat absorption.
复制标题
维生素 E 和神经功能：无β脂蛋白血症和其他脂肪吸收障碍。
DOI：
10.1002/9780470720820.ch8
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
O. H. Wolff
中科院分区：
文献类型：
--
作者：
D. Muller;J. K. Lloyd;O. H. Wolff
证据表明，维生素E是重要的正常神经功能在人类。首先，在无β-脂蛋白血症中，维生素E早期治疗可延迟并可预防神经系统并发症的发生，在已确定病变的患者中，治疗可阻止或逆转神经病变。其次，在其他脂肪吸收慢性疾病伴严重维生素E缺乏症中，维生素E可改善神经系统表现，这些表现与未经治疗的无β脂蛋白血症非常相似。因此，对于所有血清维生素E浓度低的慢性脂肪吸收不良患者，建议补充维生素E。无论病因如何，还应测量脊髓小脑疾病患者的血清维生素E浓度。
Evidence that vitamin E is important for normal neurological function in humans is presented. First, in abetalipoproteinaemia early therapy with vitamin E delays and may prevent the development of the neurological complications, and in patients with established lesions treatment can arrest or reverse the neuropathy. Second, in other chronic disorders of fat absorption with severe vitamin E deficiency, neurological manifestations which are very similar to those described in untreated abetalipoproteinaemia can be improved by vitamin E. Vitamin E supplementation is therefore advisable for all patients with chronic fat malabsorption who have low serum vitamin E concentration. Serum vitamin E concentrations should also be measured in patients with spinocerebellar disorders, whatever the aetiology.
影响因子：
15.9
作者：
MALLOY, MJ;KANE, JP;DALAL, KB
通讯作者：
DALAL, KB