Epidemiological investigation of a food-borne gastroenteritis outbreak caused by Norwalk-like virus in 30 day-care centres
Epidemiological investigation of a food-borne gastroenteritis outbreak caused by Norwalk-like virus in 30 day-care centres
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DOI：
10.1080/00365540110080133
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发表时间：
2002-01-01
影响因子：
--
通讯作者：
Ekdahl, K
中科院分区：
文献类型：
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作者：
Götz, H;De Jong, B;Ekdahl, K
1999年3月，由同一膳食供应商提供服务的30间日间护理中心爆发肠胃炎。在13个随机选择的日托中心进行了一项回顾性队列研究，以确定传播来源和模式。电镜及PCR技术证实诊断。总体发病率（AR）为37%（195/524）：儿童为30%，在成年人中。根据患者的年龄进行修改，在3月1日食用南瓜沙拉与成为早期病例相关（比值比= 3.9; 95%置信区间1.8-8.8）。在食物消耗和成为晚期病例之间没有发现显著的关联。原发性食源性AR为27%，继发性AR为14%。在5例病例、1例患病和1例无症状的食品从业人员中发现了相同的诺瓦克样病毒基因型。其中一名食品处理人员的污染似乎是病毒传播的最可能途径，并强调了严格卫生常规的重要性。
In March 1999, an outbreak of gastroenteritis occurred affecting 30 day-care centres served by the same caterer. A retrospective cohort study was performed in 13 randomly selected day-care centres to determine the source and mode of transmission. Electron microscopy and PCR were used to verify the diagnosis. The overall attack rate (AR) was 37% (195/524): 30% in children and 62%. in adults. Modified by the age of the patient, eating pumpkin salad served on I March was associated with becoming an early case (odds ratio = 3.9; 95% confidence interval 1.8-8.8). No significant association was found between food consumption and becoming a late case. The primary food-borne AR was 27% and the secondary AR was 14%. The same genotype of Norwalk-like virus was found in 5 cases and in 1 ill and 1 asymptomatic food-handler. Contamination by 1 of the food-handlers seems the most likely route of spread of the virus and underlines the importance of strict hygienic routines.