Disproportionate exercise‐induced pulmonary hypertension in relation to cardiac output in heart failure with preserved ejection fraction: a non‐invasive echocardiographic study
Disproportionate exercise‐induced pulmonary hypertension in relation to cardiac output in heart failure with preserved ejection fraction: a non‐invasive echocardiographic study
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不成比例的运动诱发的肺动脉高压与射血分数保留的心力衰竭患者的心输出量相关：一项非侵入性超声心动图研究
DOI：
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发表时间：
2023
影响因子：
18.2
通讯作者：
H. Ishii
中科院分区：
文献类型：
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作者：
Y. Saito;M. Obokata;T. Harada;Kazuki Kagami;H. Sorimachi;Naoki Yuasa;T. Kato;N. Wada;Yasuo Okumura;H. Ishii
射血分数(HFpEF)正常的心力衰竭患者常伴有肺动脉高压(PH)和肺血管重构。许多HFpEF患者对运动表现出不正常的肺血流动力学反应，这种反应在静息状态下无法识别。这可以通过平均肺动脉压-心输出量的关系(mPAP/CO斜率)无创性地估计。我们试图描述与CO(dei-PH)相关的不成比例运动性PH的病理生理学特征及其对HFpEF患者预后的影响。
Pulmonary hypertension (PH) and pulmonary vascular remodelling are common in patients with heart failure with preserved ejection fraction (HFpEF). Many patients with HFpEF demonstrate an abnormal pulmonary haemodynamic response to exercise that is not identifiable at rest. This can be estimated non‐invasively by the mean pulmonary artery pressure–cardiac output relationship (mPAP/CO slope). We sought to characterize the pathophysiology of disproportionate exercise‐induced PH in relation to CO (DEi‐PH) and its prognostic impact in patients with HFpEF.
影响因子：
24
作者：
Lam, Carolyn S. P.;Roger, Veronique L.;Rodeheffer, Richard J.;Borlaug, Barry A.;Enders, Felicity T.;Redfield, Margaret M.
通讯作者：
Redfield, Margaret M.
影响因子：
39.3
作者：
Borlaug, Barry A.;Kane, Garvan C.;Olson, Thomas P.
通讯作者：
Olson, Thomas P.