A comprehensive study of thiol reduction gene expression under stress conditions in Arabidopsis thaliana
A comprehensive study of thiol reduction gene expression under stress conditions in Arabidopsis thaliana
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DOI：
10.1111/pce.12276
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发表时间：
2015-02-01
影响因子：
7.3
通讯作者：
Reichheld, J. P.
中科院分区：
文献类型：
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作者：
Belin, C.;Bashandy, T.;Reichheld, J. P.
硫醇还原蛋白是细胞氧化还原状态的关键调节因子，管理发育和应激反应程序。在植物中，硫醇还原蛋白，即硫氧还蛋白（TRX）、谷氧还蛋白（GRX）及其各自的还原剂谷胱甘肽还原酶（GR）和硫氧还蛋白还原酶（TR）被组织在复杂的多基因家族中。为了破译不同蛋白质的功能，有必要清楚地了解它们各自的表达谱。通过从基因表达数据库收集信息，我们对拟南芥中不同类别硫醇还原基因（TRX、GRX）的所有成员的表达进行了全面的计算机研究。组织表达谱以及对许多生物和非生物胁迫条件的反应已经被系统地研究。总而言之，我们的数据的重要性是针对已发表的生化和遗传学研究进行讨论的。硫醇还原蛋白是细胞氧化还原状态的关键调节因子，管理发育和应激反应程序。在植物中，硫醇还原蛋白，即硫氧还蛋白（TRX）、谷氧还蛋白（GRX）及其各自的还原剂谷胱甘肽还原酶（GR）、硫氧还蛋白还原酶（TR）……被组织在复杂的多基因家族中。为了破译不同蛋白质的功能，有必要清楚地了解它们各自的表达谱。通过从基因表达数据库收集信息，我们对拟南芥中不同类别硫醇还原基因（TRX、GRX）的所有成员的表达进行了全面的计算机研究。组织表达谱以及对许多生物和非生物胁迫条件的反应已经被系统地研究。总而言之，我们的数据的重要性是针对已发表的生化和遗传学研究进行讨论的。
Thiol reduction proteins are key regulators of the redox state of the cell, managing development and stress response programs. In plants, thiol reduction proteins, namely thioredoxin (TRX), glutaredoxin (GRX), and their respective reducers glutathione reductase (GR) and thioredoxin reductase (TR), are organized in complex multigene families. In order to decipher the function of the different proteins, it is necessary to have a clear picture of their respective expression profiles. By collecting information from gene expression databases, we have performed a comprehensive in silico study of the expression of all members of different classes of thiol reduction genes (TRX, GRX) in Arabidopsis thaliana. Tissue expression profiles and response to many biotic and abiotic stress conditions have been studied systematically. Altogether, the significance of our data is discussed with respect to published biochemical and genetic studies.Thiol reduction proteins are key regulators of the redox state of the cell, managing development and stress response programs. In plants, thiol reduction proteins, namely thioredoxins (TRX), glutaredoxins (GRX), and their respective reducers glutathione reductases (GR), thioredoxin reductases (TR), ... are organized in complex multigene families. In order to decipher the function of the different proteins, it is necessary to have a clear picture of their respective expression profiles. By collecting information from gene expression databases, we have performed a comprehensive in silico study of the expression of all members of different classes of thiol reduction genes (TRX, GRX) in Arabidopsis thaliana. Tissue expression profiles and response to many biotic and abiotic stress conditions have been studied systematically. Altogether, the significance of our data are discussed with respect to published biochemical and genetic studies.