CARDIAC-ARRHYTHMIA - POSSIBLE COMPLICATION FROM TREATMENT WITH CISPLATIN
CARDIAC-ARRHYTHMIA - POSSIBLE COMPLICATION FROM TREATMENT WITH CISPLATIN
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DOI：
10.1177/030089168607200215
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发表时间：
1986-04-30
期刊：
影响因子：
1.9
通讯作者：
VILLANI, F
中科院分区：
文献类型：
--
作者：
CANOBBIO, L;FASSIO, T;VILLANI, F
顺铂化疗过程中很少观察到药物毒性。顺铂与足叶乙甙对心脏电活动可能的协同毒性作用进行了讨论。报告一例60岁女性肺鳞癌患者在顺铂化疗期间发生阵发性室上性心动过速。当顺铂与其他心脏毒性药物联合使用或用于心脏病患者时，应考虑潜在的心脏毒性。
Cardiotoxicity is rarely observed during cisplatin chemotherapy. A possible synergistic toxic effect of cisplatin with etoposide on cardiac electrical activity is discussed. A case of a 60-year-old woman with squamous cell lung carcinoma who developed paroxysmal supraventricular tachycardia during cisplatin chemotherapy is reported. The potential cardiotoxicity should be considered when cisplatin is combined with other cardiotoxic agents or used in patients with cardiac disease.