'Soluble' and 'insoluble' mucins - Identification of distinct populations

'Soluble' and 'insoluble' mucins - Identification of distinct populations
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DOI:
10.1042/bst0230845
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发表时间:
1995-11-01
影响因子:
3.9
通讯作者:
Davies, JR
Davies, JR
中科院分区:
生物学3区
文献类型:
--
作者:
Carlstedt, I;Herrmann, A;Davies, JR

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粘膜表面代表了身体“内部”和“外部”世界之间令人印象深刻的屏障。这一“前线”不断受到微生物、降解酶和其他有毒物质的威胁,因此,作为第一道防线,被凝胶状分泌物粘液覆盖。该生物膜的聚合物基质由高 M 糖蛋白(称为粘液糖蛋白或粘蛋白)提供。
The mucosal surfaces represent an impressive barrier between the ‘inside’of the body and the ‘outside’world. This ‘front line’is under constant threat from micro-organisms, degradative enzymes and other noxious agents and is, therefore, as a first line of defence, covered by a gellike secretion-mucus. The polymer matrix of this biofilm is provided by high-M, glycoproteins referred to as mucus glycoproteins or mucins.