Cloned cattle can be healthy and normal
Cloned cattle can be healthy and normal
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DOI：
10.1126/science.1063440
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发表时间：
2001-11-30
期刊：
影响因子：
56.9
通讯作者：
Wettstein, PJ
中科院分区：
文献类型：
--
作者：
Lanza, RP;Cibelli, JB;Wettstein, PJ
克隆人类的可能性引发了人们的疑问，即核移植能否用于繁殖健康的成年动物。大众和科学媒体上关于遗传、免疫学和其他发育问题的报道提出了这样一个问题：“是否存在任何正常的克隆”(1-4)。我们评估了一系列24头性成熟牛，这些牛是从非静止的体细胞中克隆出来的。
The possibility of cloning humans has raised questions as to whether nuclear transfer can be used to reproducibly generate healthy adult animals. Reports in the popular and scientific press on genetic, immunological, and other developmental problems raise the question of whether there are “any normal clones in existence”(1–4). We evaluated a series of 24 sexually mature cattle, cloned from nonquiescent somatic cells as described