Disease-Specific, Versus Standard, Nutritional Support for the Treatment of Pressure Ulcers in Institutionalized Older Adults: A Randomized Controlled Trial
Disease-Specific, Versus Standard, Nutritional Support for the Treatment of Pressure Ulcers in Institutionalized Older Adults: A Randomized Controlled Trial
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DOI：
10.1111/j.1532-5415.2009.02351.x
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发表时间：
2009-08-01
影响因子：
6.3
通讯作者：
Vanotti, Alfredo
中科院分区：
文献类型：
--
作者：
Cereda, Emanuele;Gini, Anna;Vanotti, Alfredo
目的：研究疾病特异性营养方法是否比标准饮食方法更有益于老年患者压疮（PU）的愈合。为期五周的随访随机对照试验（RCT）。地点：意大利科莫省的四个长期护理机构。参与者：28名患有II、III、III期压疮的老年受试者，和近期发作的IV PU干预所有28例患者均接受30 kcal/kg/d的营养支持;其中15例接受标准营养（医院饮食或标准肠内配方; 16%卡路里来自蛋白质），而13名患者接受了疾病特异性营养治疗，包括标准饮食加400 mL口服补充剂或富含蛋白质的特定肠内配方（占总热量的20%）、精氨酸、锌和维生素C（P
OBJECTIVESTo investigate whether a disease-specific nutritional approach is more beneficial than a standard dietary approach to the healing of pressure ulcers (PUs) in institutionalized elderly patients.DESIGNTwelve-week follow-up randomized controlled trial (RCT).SETTINGFour long-term care facilities in the province of Como, Italy.PARTICIPANTSTwenty-eight elderly subjects with Stage II, III, and IV PUs of recent onset (< 1-month history).INTERVENTIONAll 28 patients received 30 kcal/kg per day nutritional support; of these, 15 received standard nutrition (hospital diet or standard enteral formula; 16% calories from protein), whereas 13 were administered a disease-specific nutrition treatment consisting of the standard diet plus a 400-mL oral supplement or specific enteral formula enriched with protein (20% of the total calories), arginine, zinc, and vitamin C (P