Blood coagulation factors changes during liver regeneration in rats.
Blood coagulation factors changes during liver regeneration in rats.
复制标题
大鼠肝再生过程中凝血因子的变化。
DOI:
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复制
发表时间:
1993
期刊:
影响因子:
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通讯作者:
M. Bakic
中科院分区:
文献类型:
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作者:
J. Antovic;V. Djordjević;G. Kocić;D. Koraćević;G. Bjelaković;M. Bakic
Effects of partial hepatectomy on blood coagulation factors were investigated in rats. Analysis were performed 24, 48 and 72 hours after surgery. Howell's time was significantly higher after 24 and 48 h compared to the control value. Prothrombin time was significantly prolonged after 24 h. Partial thromboplastin time did not differ significantly in any time. FII values were significantly reduced after 24 and 48 h, but FV values only after 24 h. FVII showed significant decrease after 24 h, but significant increase at 48 h. FVIII and ATIII average values were significantly lower after 24, 48 and 72 h. Plasma fibrinogen increased. Significant differences were observed 48 and 72 h after surgery. Differences in normalization time of these coagulation factors are most probably the consequence of their synthesis in various cell types, regenerated at different periods after partial hepatectomy.
DOI:
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发表时间:
1989
期刊:
Laboratory investigation; a journal of technical methods and pathology
影响因子:
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作者:
Fausto,N;Mead,JE
通讯作者:
Mead,JE