SCINTIGRAPHIC EVALUATION OF LYMPHOMA - COMPARATIVE-STUDY OF CITRATE-GA-67 AND IN-111-BLEOMYCIN
SCINTIGRAPHIC EVALUATION OF LYMPHOMA - COMPARATIVE-STUDY OF CITRATE-GA-67 AND IN-111-BLEOMYCIN
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DOI：
10.1148/123.3.687
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发表时间：
1977-01-01
期刊：
影响因子：
19.7
通讯作者：
GOTTSCHALK, A
中科院分区：
文献类型：
--
作者：
BEKERMAN, C;MORAN, EM;GOTTSCHALK, A
对 14 名接受霍奇金病或其他淋巴瘤分期的患者进行了连续的全身扫描，使用 67Ga 柠檬酸盐和 111In 博来霉素。这些扫描的比较显示，67Ga-柠檬酸盐检测经病理证实的肿瘤部位的灵敏度为 84%，而 111In-博莱霉素仅为 56%。在 12 名患者中，Ga 扫描更清楚地显示了病变。在其他情况下，两种放射性核素的吸收量是相等的。在任何情况下，111In-博来霉素所鉴定的临床诊断或组织学证实的病变均未得到67Ga-柠檬酸盐的证实。 111In-博来霉素不能补充淋巴瘤闪烁扫描评估中的 67Ga-柠檬酸盐扫描。
Sequential whole body scans with 67Ga-citrate and 111In-bleomycin were performed for 14 patients undergoing staging for Hodgkin''s disease or other lymphomas. A comparison of these scans gave a sensitivity in detecting the pathologically proved tumor sites of 84% for 67Ga-citrate and only 56% for 111In-bleomycin. In 12 patients, the Ga scan demonstrated the lesions more clearly. In the others, the uptake of the 2 radionuclides was equal. In no case was a clinically diagnosed or histologically proved lesion identified by 111In-bleomycin that was not also demonstrated by 67Ga-citrate. 111In-bleomycin does not complement the 67Ga-citrate scan in the scintigraphic evaluation of lymphomas.