Fear of negative evaluation is associated with delusional ideation in non-clinical population and patients with schizophrenia

Fear of negative evaluation is associated with delusional ideation in non-clinical population and patients with schizophrenia
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非临床人群和精神分裂症患者对负面评价的恐惧与妄想观念相关

DOI:
10.1007/s00127-010-0237-8
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发表时间:
2011
影响因子:
4.4
通讯作者:
Harris S & Furukawa TA
Harris S & Furukawa TA
中科院分区:
医学2区
文献类型:
--
作者:
Kinoshita Y;Kingdon D;Kinoshita K;Saka K;Arisue Y;Dayson D;Nakaaki S;Fukuda K;Yoshida K;Harris S & Furukawa TA

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研究目的:最近的一些研究表明,妄想可以解释为一个连续的正常信念。对他人负面评价的恐惧(Fear of Negative Evaluation from others,FNE)是描述妄想心理过程的一个潜在因素。两组数据[来自非临床学生样本(n= 282)和精神分裂症患者(n= 117)]研究BFNE评分与21项Peters焦虑量表(PDI-21)评分之间的相关性。进行线性回归分析,以评估一旦控制了抑郁症的混杂效应,BFNE评分是否仍然与PDI-21评分相关。95%置信区间(CI)= 0.25-0.48]和患者(r= 0.33,95% CI = 0.14-0.49)样本。当抑郁症的混杂效应被控制时,这些关联仍然显著。BFNE分数的线性回归模型中的标准化系数分别为0.21在学生样本和0.19在临床sample.ConclusionsFNE与妄想性意念在非临床人群和精神分裂症患者。FNE可能是妄想患者药物和心理干预的潜在靶点。
PurposeA number of recent studies suggest that delusions may be explained as a continuum from normal beliefs. Fear of negative evaluation from others (FNE) is one of potential factors that might describe this psychological process of delusions.MethodsIn order to examine whether FNE is associated with delusional ideation in both non-clinical population and patients with schizophrenia, two sets of data [from a non-clinical student sample (n= 282) and from patients with schizophrenia (n= 117)] were collected to examine whether Brief Fear of Negative Evaluation Scale (BFNE) score and the 21-item Peters Delusions Inventory (PDI-21) score were associated with each other. Linear regression analyses were carried out to assess if the BFNE score still remained associated with the PDI-21 scores once the confounding effects of depression were controlled.ResultsBFNE scores were significantly related to PDI-21 scores in both non-clinical [Pearson product–moment correlation coefficient (r) = 0.37, 95% confidence Interval (CI) = 0.25–0.48] and patient (r= 0.33, 95% CI = 0.14–0.49) samples. These associations were still significant when confounding effects of depression were controlled. Standardised coefficients for the BFNE scores in the linear regression model were 0.21 in the student sample and 0.19 in the clinical sample.ConclusionsFNE was associated with delusional ideation both in non-clinical population and in patients with schizophrenia. FNE might be a potential target for both pharmacological and psychological interventions for patients with delusions.