New method of fixation of in-bone implanted prosthesis
New method of fixation of in-bone implanted prosthesis
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DOI：
10.1682/jrrd.2012.11.0202
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发表时间：
2013-01-01
影响因子：
--
通讯作者：
Rousse, Serge D.
中科院分区：
文献类型：
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作者：
Pitkin, Mark;Cassidy, Charles;Rousse, Serge D.
本文介绍了一种新型钛多孔复合材料皮骨一体化支架（SBIP）的有效性结果。SBIP设计用于肢体假体的直接骨骼附着，并在3只家兔的临床前研究中进行了评价。根据研究方案，将新型pylon（SBIP-3）植入3只家兔的后腿残端。SBIP-3具有侧鳍，旨在改善骨和塔架之间的结合。翼片位于骨壁中预切的两个槽内;其长度可调节以匹配骨壁的厚度。在13周（动物1）或26周（动物2和3）后，处死动物并收集样品用于组织病理学分析。鱼鳍与骨骼之间的空间被纤维血管组织和编织骨填充。我们认为，如果进一步的研究证实了目前的结果，所提出的方法可以成为一种替代既定的技术植入假体到骨髓管的托管骨。
This article presents results on the effectiveness of a new version of the titanium porous composite skin and bone integrated pylon (SBIP). The SBIP is designed for direct skeletal attachment of limb prostheses and was evaluated in a preclinical study with three rabbits. In accordance with the study protocol, a new version of the pylon (SBIP-3) was implanted into the hind leg residuum of three rabbits. The SBIP-3 has side fins that are designed to improve the bond between the bone and pylon. The fins are positioned inside two slots precut in the bone walls; their length can be adjusted to match the thickness of the bone walls. After 13 (animal 1) or 26 (animals 2 and 3) wk, the animals were sacrificed and samples collected for histopathological analysis. The space between the fins and the bone into which they were fit was filled with fibrovascular tissue and woven bone. No substantial inflammation was found. We suggest that if further studies substantiate the present results, the proposed method can become an alternative to the established technique of implanting prostheses into the medullary canal of the hosting bone.