Pre-treatment change in a randomized trial with pregnant substance-abusing women in community-based outpatient treatment
Pre-treatment change in a randomized trial with pregnant substance-abusing women in community-based outpatient treatment
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DOI:
10.1016/j.cct.2012.06.002
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发表时间:
2012-09-01
影响因子:
2.2
通讯作者:
Lewis, Daniel F.
中科院分区:
文献类型:
--
作者:
Ondersma, Steven J.;Winhusen, Theresa;Lewis, Daniel F.
Participants in clinical trials of interventions for substance use frequently show substantial pretreatment reductions in use. However, pre-treatment change has not been studied among pregnant women, a group with unique motivational characteristics. It is also not clear whether pre-treatment reduction in substance use can be clearly linked to research activities such as pretreatment assessment, or if it is the result of more general factors such as the decision to seek treatment. Using an interrupted longitudinal design, we evaluated pre-treatment change among 148 pregnant women, all of whom had completed a clinical trial comparing motivational enhancement therapy to treatment as usual. When baseline period was compared to the period after randomization and before treatment, the change in substance use was substantial (dropping from an average of substance use on 30.5% of days during baseline to 16.7% of days during the pretreatment phase; p