Computed tomography and magnetic resonance imaging features of ovarian fibrothecoma

Computed tomography and magnetic resonance imaging features of ovarian fibrothecoma
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卵巢纤维卵泡膜瘤的计算机断层扫描和磁共振成像特征

DOI:
10.3892/ol.2017.6228
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发表时间:
2017-07-01
期刊:
影响因子:
2.9
通讯作者:
Li, Dake
Li, Dake
中科院分区:
医学4区
文献类型:
--
作者:
Chen, Jingya;Wang, Jianhua;Li, Dake

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目的探讨卵巢纤维卵泡膜细胞瘤的影像学特点。回顾性分析25例经手术病理证实的卵巢纤维卵泡膜细胞瘤的临床资料。通过计算机断层扫描(CT)(n=20)和磁共振成像(MRI)(n=5)评估肿瘤的位置、大小、密度、信号强度、囊性变、钙化、强化模式和腹水。并对临床和组织学特征进行了评价。结果显示,23例(92.0%)患者为绝经后,平均年龄+/-标准差(SD)为60.7 +/- 10.8岁。所有25例肿瘤均为单侧,7例(28.0%)患者观察到子宫内膜增厚。总体而言,24例(96.0%)肿瘤边界清晰,1例(4%)肿瘤边界模糊。肿瘤的平均大小为9.8 ± 5.3 cm。16例(64.0%)为实性肿块,9例(36.0%)为囊性肿块。24例(96.0%)肿块实性区呈低密度或等密度,1例(4.0%)呈高密度。平扫图像的平均CT值(+/- SD)为44.2 +/- 12.8 HU(范围,31- 79 HU)。所有肿块在T1加权成像上均呈等信号或稍低信号,与子宫肌层相比,肿瘤实质在T2加权成像上也呈稍低信号或等信号,伴或不伴斑片状高信号区。19例行CT或MRI增强扫描,18例(94.7%)实性成分呈轻中度强化,1例(5.3%)呈强化。肿瘤大小与肿瘤囊变呈正相关(r=0.77,P
The aim of the present study was to investigate the imaging characteristics of ovarian fibrothecoma. The cases of 25 female patients with pathologically confirmed ovarian fibrothecomas were retrospectively reviewed. Tumor location, size, density, signal intensity, cystic degeneration, calcification, enhancement pattern and ascites were assessed by computed tomography (CT) (n=20) and magnetic resonance imaging (MRI) (n=5). Clinical and histological features were also evaluated. The results revealed that 23 (92.0%) patients were postmenopausal, with a mean age +/- standard deviation (SD) of 60.7 +/- 10.8 years old. All 25 tumors were unilateral and a thickened endometrium was observed in 7 (28.0%) patients. In total, 24 (96.0%) tumors appeared to have well-defined boundaries, with 1 (4%) tumor exhibiting an obscure boundary. Tumors had a mean size of 9.8 +/- 5.3 cm. Solid and predominantly solid masses were found in 16 cases (64.0%), and cystic and predominantly cystic masses were found in 9 patients (36.0%). Solid regioni of masses exhibited hypodensity or isodensity in 24 patients (96.0%), with 1 patient (4.0%) exhibiting hyperdensity. The mean CT value (+/- SD) was 44.2 +/- 12.8 HU (range, 31-79HU) in unenhanced images. All masses exhibited isointensity or slight hypointensity on T1-weighted imaging, and tumor parenchyma also exhibited slight hypointensity or isointensity on T2-weighted imaging compared with the myometrium, with or without areas of patchy hyperintensity. Contrast-enhanced CT or MRI scans were performed on 19 patients, and the solid components (94.7%) exhibited mild to moderate enhancement in 18 patients and 1 patient (5.3%) exhibited intense enhancement. Tumor size was positively correlated with the tumor cystic degeneration (r=0.77, P