Imbalance between salivary cortisol and DHEA responses is associated with social cost and self-perception to social evaluative threat in Japanese healthy young adults
Imbalance between salivary cortisol and DHEA responses is associated with social cost and self-perception to social evaluative threat in Japanese healthy young adults
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日本健康年轻人唾液皮质醇和 DHEA 反应之间的不平衡与社会成本和对社会评价威胁的自我感知有关
DOI：
10.1007/s12529-019-09835-x
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发表时间：
2020
影响因子：
2.7
通讯作者：
Yuichiro Nagano
中科院分区：
文献类型：
--
作者：
Kentaro Shirotsuki;Shuhei Izawa;Nagisa Sugaya;Kenta Kimura;Namiko Ogawa;Kosuke Chris Yamada;Yuichiro Nagano
背景社会评估性威胁激活HPA轴系统，即皮质醇和脱氢表雄酮(DHEA)反应。此外，社交焦虑的认知和行为模型表明，消极认知在维持症状中起着作用。社交焦虑是在社交情境中引起焦虑症状的。通过对44名男性受试者进行Trier社会压力测试(Trier Social Stress Test，TSST)，对社交情境中的核心负面认知--HPA轴反应、对负面评价的恐惧程度、估计的社会成本以及对其言语表现的自我知觉进行了评估。结果发现，皮质醇-脱氢表雄酮比率与受试者对言语表现的自我知觉显著相关(r=.30，p=.044)，以及自我评价与他人对言语的评价之间的差异(r=.44，p=.003)。在控制了抑郁症状后，显著的相关性仍然存在(分别为r=.39，p=.01和r=.50，p=.001)。此外，在演讲任务之前评估的社会成本估计与AUCG皮质醇(r=.38，p=.011)和皮质醇-DHEA比率(r=.40，p=.007)显著相关。结论这些结果表明，在社交场合估计社会成本，以及对压力源的扭曲自我认知，与内分泌调节失调有关。
BackgroundSocial evaluative threat activates the HPA-axis system, namely cortisol and dehydroepiandrosterone (DHEA) responses. Additionally, cognitive and behavioral models in social anxiety, which is aroused anxiety symptoms in social situations, indicate that negative cognitions have a role in the maintenance of symptoms. Thus, the present study examined the relationship between HPA-axis activity and cognitive features in social situations.MethodWe conducted the Trier Social Stress Test (TSST) with 44 male participants and assessed HPA-axis responses, fear of negative evaluation, the estimated social cost, and self-perceptions of their speech performance, which are core negative cognitions in social situations.ResultsResults revealed that the cortisol-DHEA ratio significantly correlated with self-perceptions of participants’ speech performance (r= .30,p= .044) and the discrepancy between self-ratings and others’ ratings of the speech (r= .44,p= .003). After controlling for depressive symptoms, significant correlations remained (r= .39,p= .01 andr= .50,p= .001, respectively). In addition, the estimated social cost, assessed before the speech task, significantly correlated with both the AUCg cortisol (r= .38,p= .011) and cortisol-DHEA ratios (r= .40,p= .007).ConclusionThese results suggest that estimating social costs in social situations, as well as distorted self-perceptions of that stressor, is related to dysfunctional endocrine regulation.