Incidence of adult T‐cell leukemia‐lymphoma and its familial clustering
Incidence of adult T‐cell leukemia‐lymphoma and its familial clustering
复制标题
成人T细胞白血病淋巴瘤的发病率及其家族聚集性
DOI：
--
复制
发表时间：
1985
影响因子：
6.4
通讯作者：
M. Hanaoka
中科院分区：
文献类型：
--
作者：
Toshifumi Kondo;H. Nonaka;N. Miyamoto;R. Yoshida;Y. Matsue;Yoshito Ohguchi;H. Inouye;H. Komoda;Yono Hinuma;M. Hanaoka
在乌瓦吉马区，ATLL的年发病率为每10万名40岁以上居民中有6.6名患者。该地区HTLV抗体阳性和40岁以上的人ATLL的年发病率为1例患者/1，631。在可用于系谱分析的38个家庭中观察到9个家庭发生。即使在流行区，阳性HTLV抗体的存在是非常高的ATLL家庭，这表明HTLV已代代相传，主要是在这些特定的家庭。
The yearly incidence of ATLL in the Uwajima district is 6.6 patients per 100,000 inhabitants aged over 40. The yearly morbidity rate from ATLL of persons in this district who are positive for HTLV‐antibody and older than 40 is I patient per 1,631. Familial occurrence was observed in 9/38 families available for pedigree analyses. Even in the endemic area, the existence of positive HTLV antibody is remarkably high in ATLL families, suggesting that HTLV has been transmitted from generation to generation mainly within these particular families.