Engineered nanopores for exopeptidase protein sequencing.

Engineered nanopores for exopeptidase protein sequencing.
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用于外肽酶蛋白质测序的工程纳米孔。

DOI:
10.1038/s41592-023-02136-y
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发表时间:
2024
期刊:
影响因子:
48
通讯作者:
Maglia,Giovanni
Maglia,Giovanni
中科院分区:
生物学1区
文献类型:
--
作者:
Bonini,Andrea;Sauciuc,Adina;Maglia,Giovanni

文献摘要

相似文献

两项研究表明,纳米孔可以识别20种蛋白质氨基酸及其一些翻译后修饰。再加上外肽酶,使用纳米孔的自下而上的蛋白质测序方法即将出现。
Two studies show that nanopores can identify the 20 proteinogenic amino acids and some of their post-translational modifications. Coupled with an exopeptidase, a bottom-up approach to protein sequencing using nanopores is on the horizon.