Action potential synchrony in embryonic precontractile chick heart: optical monitoring with potentiometric dyes.
Action potential synchrony in embryonic precontractile chick heart: optical monitoring with potentiometric dyes.
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胚胎预收缩鸡心的动作电位同步：用电位染料进行光学监测。
DOI：
10.1113/jphysiol.1981.sp013924
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
K. Kamino
中科院分区：
文献类型：
--
作者：
S. Fujii;A. Hirota;K. Kamino
1.用光学方法监测膜电位，在7-9只体节鸡胚胎心脏的几个不同部位同时记录到自发动作电位。2.在7-9个体节发育阶段，跳动前胚胎心脏不同区域的吸收信号类似于自发动作电位的吸收信号具有良好的同步性，这种同步性遍及心脏的整个区域。从这些实验结果可以明显看出，即使在心脏发生的早期阶段，鸡胚胎心脏细胞之间也存在电耦合。3.将胚胎心脏分为左右或前后两部分时，两半之间的动作电位同步性被完全阻断，但动作电位复发的同步性和内在节律性在每一部分都保持不变。
1. Using an optical method for monitoring membrane potential, we recorded spontaneous action potentials simultaneously in several different areas of the 7‐9 somite embryonic chick hearts. 2. Absorption signals resembling spontaneous action potentials were well synchronized among the different areas in the prebeating embryonic heart during the 7‐9 somite stages of development, and the synchronization spread over the entire area of the heart. From these experimental results, it is evident that there is electrical coupling among embryonic chick heart cells even in the early stages of cardiogenesis. 3. When an embryonic heart was separated into right and left or anterior and posterior parts, the action potential synchrony between the two halves was completely blocked; however, the synchrony and the intrinsic rhythmicity in action potential recurrence remained in each part.