Context-specific adaptation of the gain of the oculomotor response to lateral translation using roll and pitch head tilts as contexts.
Context-specific adaptation of the gain of the oculomotor response to lateral translation using roll and pitch head tilts as contexts.
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使用滚动和俯仰头部倾斜作为上下文，对动眼神经反应的增益进行上下文特定的适应以进行横向平移。
DOI：
10.1007/s00221-002-1235-1
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Patel,Vivek
中科院分区：
文献类型：
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作者：
Shelhamer,Mark;Peng,GraceCY;Ramat,Stefano;Patel,Vivek
以前的研究证实，前庭和眼球运动行为可以同时具有两种适应状态(例如，增益)，并且上下文线索(例如，垂直眼睛位置)可以在这两种状态之间切换。本研究考察了对耳间平移(我们称之为“线性前庭-眼反射”或LVOR，尽管它可能有前庭外成分)的眼动反应的这种特定于语境的适应现象。受试者直立坐在线性雪橇上，以0.7赫兹和0.3G峰值加速度平移，同时使用视觉-前庭失配范式自适应地增加(×2)或减少(×0)LVOR的增益。在每一次实验中，在一种情况下要求增加增益，在另一种情况下要求降低增益。在黑暗中对适应前后的步长和正弦进行测试，在每个背景下评估背景本身能够回忆起适应期间强加在该背景中的增益状态的程度。使用了两种不同的环境：头部俯仰(26°向前和向后)和头部侧滚(26°或45°，左右)。头部滚动倾斜可以很好地作为一种背景提示：头部向右滚动时，LVOR可以比头部向左滚动时有更高的增益。头部倾斜度作为上下文线索的效果较差。这表明，语境线索与被适应的反应越密切，它就越有效。
Previous studies established that vestibular and oculomotor behaviors can have two adapted states (e.g., gain) simultaneously, and that a context cue (e.g., vertical eye position) can switch between the two states. The present study examined this phenomenon ofcontext-specific adaptationfor the oculomotor response to interaural translation (which we term “linear vestibulo-ocular reflex” or LVOR even though it may have extravestibular components). Subjects sat upright on a linear sled and were translated at 0.7 Hz and 0.3gpeak acceleration while a visual-vestibular mismatch paradigm was used to adaptively increase (×2) or decrease (×0) the gain of the LVOR. In each experimental session, gain increase was asked for in one context, and gain decrease in another context. Testing in darkness with steps and sines before and after adaptation, in each context, assessed the extent to which the context itself could recall the gain state that was imposed in that context during adaptation. Two different contexts were used: head pitch (26° forward and backward) and head roll (26° or 45°, right and left). Head roll tilt worked well as a context cue: with the head rolled to the right the LVOR could be made to have a higher gain than with the head rolled to the left. Head pitch tilt was less effective as a context cue. This suggests that the more closely related a context cue is to the response being adapted, the more effective it is.