Is there a difference between hare syphilis and rabbit syphilis? Cross infection experiments between rabbits and hares
Is there a difference between hare syphilis and rabbit syphilis? Cross infection experiments between rabbits and hares
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DOI：
10.1016/j.vetmic.2013.02.001
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发表时间：
2013-05-31
影响因子：
3.3
通讯作者：
Smajs, David
中科院分区：
文献类型：
--
作者：
Lumeij, Johannes T.;Mikalova, Lenka;Smajs, David
用兔源性副猪密螺旋体及兔源性相关微生物（暂命名为“副猪密螺旋体”）交叉感染家兔和野兔，结果表明，兔源性副猪密螺旋体与兔源性相关微生物交叉感染家兔和野兔。兔副驴蹄吸虫病在临床上影响家兔，但只引起野兔的血清转化而不引起临床疾病，而“T.副铝孔菌”在兔子和野兔中均诱发疾病。16S rRNA基因的克隆。对”副铝孔菌“进行测序（GenBank acc.no.JX899416），并与T.副驴蹄吸虫菌株Cuniculi A.根据2002 bp的序列比对，构建了几株密螺旋体的系统发育树。两个都是T。paraluisleporis”和T. paraluiscuniculi聚集在一起，表明它们的共同起源。这两个代表的密切的系统发育相关性支持的结论，亚种或生态变种的地位，而不是种的地位，这些菌株。一个更合适的物种名称可能是副luisleporidarum密螺旋体。属格指的是主格Leporidae（兔子和野兔）。在兔子身上自然发生的菌株应该是T。paraluisleporidarum ecovar Cuniculus和野兔T.兔由于前者的生理宿主较少，因此兔形变种可能是兔形变种的进化祖先。(C)2013年由Elsevier B.V.出版
Cross infection of rabbits and hares with Treponema paraluiscuniculi from rabbits and the related microorganism from hares, which was provisionally named "Treponema paraluisleporis", revealed that T. paraluiscuniculi affects rabbits clinically, but only causes seroconversion in hares without causing clinical disease, while "T. paraluisleporis" induces disease in both rabbits and hares. The 16S rRNA gene of "T. paraluisleporis" was sequenced (GenBank acc. no. JX899416) and compared to the sequence of T. paraluiscuniculi strain Cuniculi A. A phylogenetic tree based on the sequence alignment of 2002 bp taken from several treponemal strains was constructed. Both "T. paraluisleporis" and T. paraluiscuniculi are clustered together indicating their common origin. The close phylogenetic relatedness of both representatives supports the conclusion that subspecies or ecovar status should be given to these strains rather than species status. A more appropriate species name might be Treponema paraluisleporidarum. The genitive refers to the nominative Leporidae (family of rabbits and hares). The naturally occurring strain in rabbits would than be T. paraluisleporidarum ecovar Cuniculus and the strain from hares T. paraluisleporidarum ecovar Lepus. Since the former seems to have fewer physiological hosts, ecovar Lepus may represent an evolutionary ancestor of ecovar Cuniculus. (C) 2013 Published by Elsevier B.V.