Temperature and Dengue Virus Infection in Mosquitoes: Independent Effects on the Immature and Adult Stages
Temperature and Dengue Virus Infection in Mosquitoes: Independent Effects on the Immature and Adult Stages
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DOI：
10.4269/ajtmh.12-0421
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发表时间：
2013-03-01
影响因子：
3.3
通讯作者：
Bettinardi, David
中科院分区：
文献类型：
--
作者：
Alto, Barry W.;Bettinardi, David
温度是影响蚊子生物学过程的最重要的环境因素之一，包括它们与病毒的相互作用。在这些研究中，我们表现出独立的饲养温度的影响，不成熟的水生阶段和成人陆地阶段的保持温度在亚洲虎蚊伊蚊（Stegomyia）albopictus的成年人的生存和登革热-1病毒感染的进展方面的改变。我们的研究表明，成人的生存是由成人持有的温度，无论饲养条件的未成熟阶段。相反，当未成熟阶段在凉爽条件下饲养时，病毒在蚊子体内的传播（传播的先决条件）减少了。这些结果表明，不成熟的饲养温度选择性地修改蚊子的性状，影响能力的病毒，他们进一步了解温度的性质影响蚊子和病毒病原体之间的相互作用和疾病传播的风险。
Temperature is one of the most important environmental factors affecting biological processes of mosquitoes, including their interactions with viruses. In these studies, we show independent effects of rearing temperature on the immature aquatic stages and holding temperature on the adult terrestrial stage in terms of alterations in adult survival and progression of dengue-1 virus infection in the Asian tiger mosquito Aedes (Stegomyia) albopictus. Our studies show that adult survival was determined by adult-holding temperature, regardless of rearing conditions of the immature stages. In contrast, spread of virus throughout the body of the mosquito, a pre-requisite for transmission, was reduced when the immature stages were reared in cool conditions. These results show that immature-rearing temperature selectively modified mosquito traits that influence competency for viruses, and they further our understanding of the nature of temperature effects on interactions between mosquitoes and virus pathogens and risk of disease transmission.