Diabetic Foot Gangrene Patient with Multi-drug Resistant Pseudomonas Putida Infection in Karawaci District, Indonesia.
Diabetic Foot Gangrene Patient with Multi-drug Resistant Pseudomonas Putida Infection in Karawaci District, Indonesia.
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DOI：
10.4103/0974-777x.146378
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发表时间：
2015-01
影响因子：
1.6
通讯作者：
Tjiang MM
中科院分区：
文献类型：
--
作者：
Hardjo Lugito NP;Nawangsih C;Moksidy JC;Kurniawan A;Tjiang MM
恶臭假单胞菌是一种杆状、非发酵的革兰氏阴性微生物，常发现于利用需氧代谢的环境中，以前认为其致病性较低。它已被报道为皮肤和软组织感染的原因，特别是在免疫功能低下的患者中。一位绿色杂货店女店主，51岁，自1个月前因第1、第2和第3趾坏疽和骨髓炎以及右脚底伤口来内科门诊就诊。患者自一年前开始有未受控制的糖尿病病史。根据经验给予头孢曲松2 g b.i.d，甲硝唑500 mg t.i.d，然后给予阿米卡星250 mg b.i.d，随后进行手指截肢和伤口清创。脓液微生物培养显示为多重耐药的恶臭假单胞菌。经过抗生素和手术后，她恢复得很好。
Pseudomonas putida is a rod-shaped, non fermenting Gram-negative organism frequently found in the environment that utilizes aerobic metabolism, previously thought to be of low pathogenicity. It had been reported as cause of skin and soft tissue infection, especially in immunocompromised patients. A female green grocer, 51 year-old came to internal medicine out-patient clinic with gangrene and osteomyelitis on her 1st, 2nd and 3rd digit and wound on the sole of the right foot since 1 month prior. The patient had history of uncontrolled diabetes since a year ago. She was given ceftriaxone 2 grams b.i.d, metronidazole 500 mg t.i.d empirically and then amikacin 250 mg b.i.d, followed by amputation of the digits and wound debridement. The microorganism's culture from pus revealed multi drug resistant Pseudomonas putida. She recovered well after antibiotics and surgery.