SELECTIVE FACILITATION OF DIFFERENT HAND MUSCLES BY SINGLE CORTICOSPINAL NEURONS IN THE CONSCIOUS MONKEY
SELECTIVE FACILITATION OF DIFFERENT HAND MUSCLES BY SINGLE CORTICOSPINAL NEURONS IN THE CONSCIOUS MONKEY
复制标题
DOI：
10.1113/jphysiol.1986.sp016342
复制
发表时间：
1986-12-01
影响因子：
5.5
通讯作者：
MUIR, RB
中科院分区：
文献类型：
--
作者：
BUYS, EJ;LEMON, RN;MUIR, RB
1. 峰值后的 e.m.g. 促进已经在不同的手和前臂肌肉中研究了猴子运动皮层神经元的活动。 2. 同时记录 78 个神经元和 5 到 10 个不同的肌肉。通过至少一根测试肌肉的尖峰触发平均值中存在尖峰后促进，将 47 个神经元确定为皮质运动神经元。 3. 在猴子执行精确抓握任务期间，所有 47 个皮质运动神经元的活动均明显增加，并且所有这些神经元都与样本肌肉共同激活。 4. 为了评估从单个皮质运动神经元到不同肌肉的促进差异，用所有同时记录的肌肉构建了尖峰触发平均值。样本中的肌肉数量以及表现出尖峰后促进作用的肌肉数量通过排除任何可能由不同对肌电图对之间的串扰而产生的尖峰后促进作用进行校正。电极。 5. 大多数皮质运动神经元在有限数量的测试肌肉中产生尖峰后促进。每个皮质运动细胞的峰值后促进肌肉的平均数量从 1.4 .+- 上升。当对五块肌肉进行采样至 2.0 .+- 时，为 0.5 (S.D.)。当采样十个时为 1.5。平均而言，每个皮质运动神经元在 27% 的测试肌肉中产生峰后促进作用。四十七个皮质运动神经元中只有三个对一半或更多的测试肌肉提供了后脉冲促进。 6.当从皮质运动细胞和肌电图构建尖峰触发平均值时，用给定皮质运动神经元采样的肌肉中尖峰后促进的分布模式没有改变。在精确握力任务的两个不同阶段或在执行完全不同的强力握力任务期间记录的活动。 7. 在两个或多个不同肌肉中产生后脉冲促进的皮质运动细胞通常在具有协同功能的肌肉中这样做。 8. 有人提出，皮质运动神经元可能通过选择性促进手部肌肉而导致相对独立的手指运动，从而导致肌肉活动的分级模式。
1. Post-spike facilitation of e.m.g. activity by monkey motor cortex neurones has been investigated in different hand and forearm muscles. 2. Seventy-eight neurones were recorded concurrently with between five and ten different muscles. Forty-seven neurones were identified as a cortico-motor by the presence of post-spike facilitation in the spike-triggered average of at least one of the tested muscles. 3. All forty-seven cortico-motor neurones showed clear increases in activity during performance of a precision grip task by the monkey, and all of them were co-activated with the sampled muscles. 4. To assess the divergence of facilitation from a single cortico-motor neurone to different muscles, spike-triggered averages were constructed with all of the concurrently recorded muscles. The number of muscles in the sample, and the number of muscles showing post-spike facilitation, were corrected by excluding any post-spike facilitation which could have arisen by cross-talk between the different pairs of e.m.g. electrodes. 5. Most cortico-motor neurones produced post-spike facilitation in a restricted number of tested muscles. The mean number of post-spike facilitation-bearing muscles per cortico-motor cell rose from 1.4 .+-. 0.5 (S.D.) when five muscles were sampled to 2.0 .+-. 1.5 when ten were sampled. On average, each cortico-motor neurone produced post-spike facilitation in 27% of the tested muscles. Only three of forty-seven cortico motor neurones gave post-spike facilitation in half or more of the tested muscles. 6. The distribution pattern of post-spike facilitation among the muscles sampled with a given cortico-motor neurone was not altered when the spike-triggered averages were constructed from cortico-motor cell and e.m.g. activity recorded during two different phases of the precision grip task, or during performance of a quite different, power grip, task. 7. Cortico-motor cells which produced post-spike facilitation in two or more different muscles often did so in muscles with synergistic functions. 8. It is suggested that cortico-motor neurones may contribute to relatively independent finger movements by virtue of their selective facilitation of hand muscles leading to a fractionated pattern of muscle activity.