Error optimization of a three-dimensional magnetic resonance imaging tagging-based cartilage deformation technique
Error optimization of a three-dimensional magnetic resonance imaging tagging-based cartilage deformation technique
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DOI：
10.1002/mrm.20669
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发表时间：
2005-11-01
影响因子：
3.3
通讯作者：
Walton, JH
中科院分区：
文献类型：
--
作者：
Neu, CP;Hull, ML;Walton, JH
三维应变场在关节软骨受到压缩负荷，可以确定使用最近开发的基于MRI的软骨变形的标签注册技术。本研究的目的是确定实验变量，最大限度地减少技术误差，这是以前没有报道。使用直接实验和Monte Carlo模拟确定四个变量的误差（应变偏倚和精密度）：空间分辨率、标记线间距、施加的标称应变和用于描述B样条模型中标记线的控制点数量。重要的结果包括：（1）偏差与零无显著差异，（2）精度随图像分辨率和标记线间距增加，（3）精度与施加的标称应变无关，（4）误差最小（绝对精度= 0.41%应变）：空间分辨率= 0.05 X 0.05 mm（2）;标记线间距= 2.0 mm;控制点= 6。有了这些结果，该技术现在可以在各种应用中使用，同时最大限度地减少误差。
Three-dimensional strain fields in articular cartilage subjected to compressive loading can be determined using a recently developed MRI-based cartilage deformation by tag registration technique. The objective of this study was to determine the experimental variables that minimize the technique error, which has not been previously reported. Error (strain bias and precision) was determined using direct experiments and Monte Carlo simulations for four variables: spatial resolution, tag line spacing, applied nominal strain, and number of control points used to describe tag lines in a B-spline model. The important results include the following: (1) bias was not significantly different from zero, (2) precision increased with image resolution and with tag line spacing, (3) precision was independent of applied nominal strain, and (4) error was a minimum (absolute precision = 0.41% strain) for the following values: spatial resolution = 0.05 X 0.05 mm(2); tag line spacing = 2.0 mm; control points = 6. With these results the technique can now be used in various applications while minimizing error.