REGRESSION TECHNIQUES FOR THE DETECTION OF ANALYTICAL BIAS

REGRESSION TECHNIQUES FOR THE DETECTION OF ANALYTICAL BIAS
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DOI:
10.1039/an9871200377
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发表时间:
1987-04-01
期刊:
影响因子:
4.2
通讯作者:
THOMPSON, M
THOMPSON, M
中科院分区:
化学2区
文献类型:
--
作者:
RIPLEY, BD;THOMPSON, M

文献摘要

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回归技术通常用于比较几种浓度下的两种分析方法,并测试一种方法相对于另一种方法的偏倚。然而,只有当一种方法没有错误时,回归才严格适用,例如与参考材料进行比较。一个类似回归的技术,最大似然拟合的函数关系(MLFR),解释,并证明工作良好。在某些条件下,加权回归提供了一个很好的近似MLFR,所以可以使用,如果更方便。
Regression techniques are commonly applied to compare two analytical methods at several concentrations and to test the biases of one method relative to another. However, regression is strictly applicable only when one method is without error, for example in comparisons with reference materials. A regression-like technique, maximum-likelihood fitting of a functional relationship (MLFR), is explained and is demonstrated to work well. Under some conditions weighted regression provides a good approximation to MLFR, and so can be used if more convenient.