Structure-function relationships in the primate superior colliculus. II. Morphological identity of presaccadic neurons.
Structure-function relationships in the primate superior colliculus. II. Morphological identity of presaccadic neurons.
复制标题
灵长类动物上丘的结构与功能关系。
DOI：
--
复制
发表时间：
1988
影响因子：
2.5
通讯作者：
S. Highstein
中科院分区：
文献类型：
--
作者：
A. Moschovakis;A. Karabelas;S. Highstein
1.将辣根过氧化物酶（HRP）微电极插入警觉的松鼠猴的上级丘（SC）。自发性眼球运动进行监测，在黑暗中记录和轴突内注射的纤维进行preaccadic信号。2.神经元活动与扫视参数之间的关系的分析表明，扫视相关神经元可以在功能上分为：1）矢量长导联爆发神经元（n = 31），和2）方向长导联爆发神经元。3.矢状面长导联爆发神经元在自发性扫视前在其运动区内几乎没有自发性活动，爆发强度大，潜伏期约为20 ms，其胞体大部分（4/5）位于SC的视层。连同它们的运动场与更深的顶盖层的运动图的现有描述是一致的。由于它们的体树突形态和轴突轨迹的模式，TLLB属于我们的同伴报告中描述的顶盖传出神经元的T组。通过其分支的轴突系统，每个TLLB可以中继信号编码预期的眼位移的前背束（PDB），对侧顶盖，同侧中脑网状结构（MRF），并rostrally位于同侧的SC的目标，除了参与顶盖内的信息处理的网状目标。4.与自发性扫视无关的活动的覆盖的顶盖神经元（n = 4）参与的背侧和腹侧升离顶盖束，以及同侧中脑网状结构的投影。它们不参与SC的连合投射，也不需要有复发性侧支循环。由于它们的体树突形态和轴突轨迹的模式，这些细胞属于X组顶盖传出神经元，在前面的文章中描述。5.起源于SC（n = 5）记录的定向长引线爆裂纤维的vulvered细胞位于MRF的tectoreceptor部分，它们的轴突终末完全包含在SC内。这些网状顶盖长引线爆裂神经元（RTLLB）的放电的高频部分先于大多数逆向扫视约19 ms。（400字处截断摘要）
1. Microelectrodes filled with horseradish peroxidase (HRP) were inserted in the superior colliculus (SC) of alert squirrel monkeys. Spontaneous eye movements were monitored in the dark during recording and intraaxonal injection of fibers carrying presaccadic signals. 2. Analysis of the relationship between neuronal activity and saccadic parameters indicates that saccade-related neurons can be functionally classified into: 1) vectorial long-lead burst neurons (n = 31), and 2) directional long-lead burst neurons. 3. Vectorial long-lead burst neurons have little if any spontaneous activity and burst intensely before spontaneous saccades within their movement fields with a latency of approximately 20 ms. Their cell bodies were recovered mostly (4/5) in the stratum opticum of the SC. The mediolateral and anteroposterior location of these tectal long-lead burst neurons (TLLBs) together with their movement fields are consistent with existing descriptions of the motor map of the deeper tectal layers. Due to their somatodendritic morphology and pattern of axonal trajectories, TLLBs belong to the T group of tectal efferent neurons that was described in our companion report. Through its branched axonal system each TLLB can relay a signal coding intended eye displacement to reticular targets of the predorsal bundle (PDB), contralateral tectum, ipsilateral mesencephalic reticular formation (MRF), and rostrally located ipsilateral targets of the SC, besides participating in intratectal information processing. 4. Recovered tectal neurons (n = 4) with activity not related to spontaneous saccades participate in the predorsal and ventral ascending tectofugal bundles as well as the projection to the ipsilateral mesencephalic reticular formation. They do not participate in the commissural projection of the SC and need not have recurrent collaterals. Due to their somatodendritic morphology and pattern of axonal trajectories, these cells belong to the X group of tectal efferent neurons that was described in the preceding paper. 5. Recovered cells of origin of directional long-lead burst fibers recorded in the SC (n = 5) are located in the tectorecipient portion of the MRF and their axonal terminals are entirely contained within the SC. The high-frequency portion of the discharge of these reticulotectal long-lead burst neurons (RTLLBs) precedes most contraversive saccades by approximately 19 ms.(ABSTRACT TRUNCATED AT 400 WORDS)