Hyperferritinemia in malignant histiocytosis and virus-associated hemophagocytic syndrome.
Hyperferritinemia in malignant histiocytosis and virus-associated hemophagocytic syndrome.
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恶性组织细胞增多症和病毒相关噬血细胞综合征中的高铁蛋白血症。
DOI：
10.1056/nejm198702053160617
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发表时间：
1987
影响因子：
158.5
通讯作者：
S. Imashuku
中科院分区：
文献类型：
--
作者：
N. Esumi;S. Ikushima;S. Todo;S. Imashuku
编辑：血清铁蛋白水平在许多疾病情况下都会升高，包括铁负荷过高、肝脏炎症或损害，以及恶性疾病，如霍奇金氏病、1例神经母细胞瘤、2例白血病、3例和其他癌症。4 1984年，Andreesen et al.5表明，在体外单核细胞向巨噬细胞成熟的过程中，细胞内铁蛋白水平增加了约100倍。沃伍德等人。6报道称，培养的单个核细胞维持在含铁的培养液中或在吞噬红细胞的过程中迅速积聚铁蛋白，提示吞噬细胞可能是血清铁蛋白的重要来源。然而，很少有临床数据描述血清…，400字以下的文章没有摘录。
To the Editor: Serum ferritin levels are increased in many disease conditions, including iron overload, hepatic inflammation or damage, and malignant disorders, such as Hodgkin's disease, 1 neuroblastoma, 2 leukemia, 3 and other cancers. 4 In 1984, Andreesen et al. 5 demonstrated that intracellular levels of ferritin increased about 100-fold during the maturation of monocytes into macrophages in vitro. Worwood et al. 6 reported that cultured mononuclear cells that were maintained in iron-containing medium or were in the process of phagocytizing red cells rapidly accumulated ferritin, suggesting that phagocytic cells may be an important source of serum ferritin. There are, however, few clinical data describing serum…, No extract is available for articles shorter than 400 words.