How small are the smallest selectable domains of form?
How small are the smallest selectable domains of form?
复制标题
最小的可选形式域有多小？
DOI：
10.1093/genetics/130.2.345
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发表时间：
1992
期刊：
影响因子：
3.3
通讯作者：
Weber,KE
中科院分区：
文献类型：
--
作者：
Weber,KE
从同一基础种群中选择了两个品系，在两个很小(小于0.2 mm)和紧密相邻(小于0.3 mm)的翼基内产生同时的拮抗变化。目标区域附近的机翼尺寸因大的正负百分比差异而变得不同，而机翼其余部分只发生了很小的均匀百分比变化。如果非常小的形态区域(横跨不到100个细胞)可以几乎独立地对选择做出反应，即使是在小的人口样本中，那么对发育细节的控制必须涉及许多基因，而且发育和适应的可能结果的多样性一定很大。
Two lines of Drosophila melanogaster from the same base population were selected in opposite directions to produce simultaneous antagonistic changes in two very small (less than 0.2 mm) and closely adjacent (less than 0.3 mm) dimensions within the base of the wing. Wing dimensions near the targeted area became differentiated by large positive and negative percentage differences, while only small homogeneous percentage changes occurred in the remainder of the wing. If very small regions of morphology (less than 100 cells across) can respond to selection almost independently, even in small population samples, then the control of developmental detail must involve many genes, and the diversity of possible outcomes in development and adaptation must be large.