Family-focused treatment for childhood-onset depressive disorders: results of an open trial.
Family-focused treatment for childhood-onset depressive disorders: results of an open trial.
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DOI：
10.1177/1359104507078474
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发表时间：
2007-07-01
影响因子：
1.8
通讯作者：
Asarnow, Joan R
中科院分区：
文献类型：
--
作者：
Tompson, Martha C;Pierre, Claudette B;Asarnow, Joan R
研究目的是为抑郁学龄儿童制定一份以家庭为中心的干预治疗手册，评估其可行性和可接受性，并完成一项初步的开放试验，以检查治疗效果。9名符合抑郁症标准的年轻人（重度抑郁症、心境恶劣障碍或抑郁症，未另行说明）完成了为期12周的家庭干预，并在治疗完成后立即和9个月进行评估。干预措施提出了一个如何维持抑郁症状的人际关系模型，并强调制定改变人际关系过程的家庭战略，支持恢复和增强复原力。治疗后，66%的年轻人从抑郁发作中康复;治疗后9个月，77%的人康复。注意到全球运作情况有了重大改善。在随访期间没有复发，在干预或随访期间没有自杀行为。母亲和父亲的儿童行为检查表报告和儿童的自我报告表明，显着的症状减轻。探索性的分析表明，父母经常批评的年轻人特别受益。以家庭为中心的干预儿童期发作的抑郁症表现出类似的收益与经验支持的治疗抑郁症的青少年和上级的抑郁症结果的自然主义研究中看到的。这一有利的风险/获益特征支持了随机对照试验的价值。
Study objectives were to develop a treatment manual for a family-focused intervention for depressed school-aged children, evaluate its feasibility and acceptability, and complete an initial open trial to examine treatment effects. Nine young people meeting criteria for depression (major depressive disorder, dysthymic disorder, or depression not otherwise specified), completed a 12-week family intervention, and were assessed immediately and at 9 months following treatment completion. The intervention presented an interpersonal model of how depressive symptoms are maintained, and emphasized developing family strategies for altering interpersonal processes, supporting recovery and enhancing resilience. At posttreatment 66% of the young people had recovered from their depressive episodes; by 9 months posttreatment 77% had recovered. Significant improvements in global functioning were noted. There were no relapses in the follow-up period and no instances of suicidal behavior during the intervention or follow-up. Mothers' and fathers' Child Behavior Checklist reports and children's self reports indicated significant symptom reductions. Exploratory analyses suggest particular benefit for young people with parents high in criticism. The family-focused intervention for childhood-onset depression demonstrated gains similar to those seen with empirically supported treatments for depressed adolescents and superior to those seen in naturalistic studies of depression outcomes. This favorable risk/benefit profile supports the value of a randomized controlled trial.