Multiple complex coronary atherosclerosis in diabetic patients with acute myocardial infarction: a three-vessel optical coherence tomography study
Multiple complex coronary atherosclerosis in diabetic patients with acute myocardial infarction: a three-vessel optical coherence tomography study
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DOI：
10.4244/eijv8i8a145
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发表时间：
2012-12-01
期刊：
影响因子：
6.2
通讯作者：
Masuyama, Tohru
中科院分区：
文献类型：
--
作者：
Fukunaga, Masashi;Fujii, Kenichi;Masuyama, Tohru
目的：急性心肌梗死（AMI）的主要原因是薄帽纤维粥样瘤（TCFA）的破坏和随后的血栓形成。心血管事件导致糖尿病患者死亡率增加；糖尿病患者和非糖尿病患者的易损斑块可能存在差异。我们使用光学相干断层扫描（OCT）来评估糖尿病AMI患者易损斑块的发生率。方法与结果：对70例AMI患者的三条主要冠状动脉行OCT检查，其中非糖尿病患者48例，糖尿病患者22例。TCFA的OCT标准是存在富含脂质的斑块组成和纤维化帽厚度
Aims: The main cause of acute myocardial infarction (AMI) is the disruption of a thin-cap fibroatheroma (TCFA) and subsequent thrombosis. Mortality increases in diabetic patients due to cardiovascular events; there may be differences in the vulnerable plaques between diabetic and non-diabetic patients. We used optical coherence tomography (OCT) to assess the incidence of vulnerable plaques in diabetic patients with AMI.Methods and results: OCT was performed in all three major coronary arteries of 70 AMI patients: 48 nondiabetic and 22 diabetic patients. The OCT criterion for TCFA was the presence of both a lipid-rich plaque composition and a fibrotic cap thickness of