Viruses can cause disease in the absence of morphological evidence of cell injury: implication for uncovering new diseases in the future.
Viruses can cause disease in the absence of morphological evidence of cell injury: implication for uncovering new diseases in the future.
复制标题
在没有细胞损伤的形态学证据的情况下，病毒可以引起疾病：对未来发现新疾病的启示。
DOI：
10.1093/infdis/159.3.384
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Oldstone,MB
中科院分区：
文献类型：
--
作者：
Oldstone,MB
病毒可以在分化的细胞中复制，通过改变细胞产生特殊产物的能力，如内分泌激素、神经递质和淋巴因子。从系统角度来看，结果可能是体内平衡失衡，导致内分泌、神经、免疫或其他系统疾病，通常在没有可检测到的细胞破坏的情况下发生。
A virus can replicate in differentiated cells, there by altering their ability to make specialized products such as endocrine hormones, neurotransmitters, and lymphokines. Systemically, the outcome can be an imbalance in homeostasis, resulting in diseases of the endocrine, nervous, immune, or other systems, frequentlyin the absence of detectable cell destruction.