Toward a Complex Network of Risks for Psychosis: Combining Trauma, Cognitive Biases, Depression, and Psychotic-like Experiences on a Large Sample of Young Adults
Toward a Complex Network of Risks for Psychosis: Combining Trauma, Cognitive Biases, Depression, and Psychotic-like Experiences on a Large Sample of Young Adults
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DOI：
10.1093/schbul/sbaa125
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发表时间：
2021-03-01
影响因子：
6.6
通讯作者：
Frydecka, Dorota
中科院分区：
文献类型：
--
作者：
Gaweda, Lukasz;Pionke, Renata;Frydecka, Dorota
尽管创伤性生活事件和类精神病经历（ple）之间的联系已经确立，但对这种关系的潜在机制的了解却很少。本研究的目的是通过考虑认知偏差和抑郁症状在青年成人（18-35岁，M = 26.52, SD = 4.74, n = 6772）中的作用，更好地了解创伤性生活事件与创伤性生活事件之间的联系结构。我们的研究是在网络分析的框架内进行的。采用前驱症状问卷（PQ-16）测量幸福感，采用达沃斯认知偏差评估量表-18 （DACOBS-18）中的9个项目测量认知偏差，采用流行病学研究中心抑郁量表（csd - r）评估抑郁症状，采用童年照顾和虐待经历问卷（CECA.Q）和创伤经历清单（TEC）组合测量创伤性生活事件暴露。结果显示所有节点在域内和域之间相互连接的网络，没有孤立的因素。性创伤暴露是网络中最中心的节点。通过认知偏差和抑郁症状确定了从创伤到ple的途径。然而，最核心的创伤性生活事件与ple之间的最短路径是通过其他创伤性生活事件，在此过程中没有认知偏差或抑郁症状。我们的研究结果表明，环境逆境以及功能失调的信息处理和抑郁在精神病风险网络中的重要性。
Although the linkage between traumatic life events and psychotic-like experiences (PLEs) is well established, the knowledge of potential mechanisms of this relationship is scarce. The aim of the present study was to better understand the structure of connections between traumatic life events and PLEs by considering at the same time the role of cognitive biases and depressive symptoms in the population of young adults (18-35 years of age, M = 26.52, SD = 4.74, n = 6772). Our study was conducted within a framework of network analysis. PLEs were measured with the Prodromal Questionnaire (PQ-16), cognitive biases were measured with nine items from the Davos Assessment of Cognitive Biases Scale-18 (DACOBS-18), depressive symptoms were assessed with the Center for Epidemiologic Studies-Depression Scale (CESD-R) and exposure to traumatic life events was measured with a combination of Childhood Experience of Care and Abuse Questionnaire (CECA.Q) and Traumatic Experience Checklist (TEC). The results present a network of all nodes being interconnected within and between domains, with no isolated factors. Exposures to sexual trauma were the most central node in the network. Pathways were identified from trauma to PLEs via cognitive biases and depressive symptoms. However, the shortest pathway between the most central traumatic life event and PLEs was through other traumatic life events, without cognitive biases or depressive symptoms along the way. Our findings suggest the importance of environmental adversities as well as dysfunctional information processing and depression in the network of psychosis risks.