Extraction, quantification and characterization of uterine magnetomyographic activity-A proof of concept case study
Extraction, quantification and characterization of uterine magnetomyographic activity-A proof of concept case study
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DOI：
10.1016/j.ejogrb.2009.02.023
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发表时间：
2009-05-01
影响因子：
2.6
通讯作者：
Preissl, Hubert T.
中科院分区：
文献类型：
--
作者：
Eswaran, Hari;Govindan, Rathinaswamy B.;Preissl, Hubert T.
目的：其目的是提取，量化和表征子宫磁（MMG）信号，对应于子宫的电生理activityoftheuterase.Methods：经腹MMG记录与高时空分辨率进行了使用的151非侵入性磁传感器系统。提取，定量和表征程序的开发和应用到有代表性的MMG信号，记录从一个孕妇在怀孕37周开始，直到受试者达到活跃labor.Results的定期间隔：多个MMG记录成功地进行了主题之前，她进入活跃的劳动。提取的MMG爆发活动显示出与母亲感知的收缩事件的统计学显著相关性（r = 0.2; p < 0.001）。时频分析显示，与早期记录相比，在被试进入活跃分娩前48 h，爆发活动的功率向高频移动。此外，有一个逐渐增加的同步性在较高的频率带的主题达到接近活跃labor.Conclusions：非侵入性记录的磁信号的妊娠子宫具有高的时空分辨率可以提供一个洞察到准备阶段的劳动力，并有潜力预测长期和早产。(c)2009爱思唯尔爱尔兰有限公司保留所有权利。
Objective: The objective was to extract, quantify and characterize the uterine magnetomyographic (MMG) signals that correspond to the electrophysiological activity of the uterus.Methods: Transabdominal MMG recordings with high spatial-temporal resolution were performed with the use of the 151 non-invasive magnetic sensor system. The extraction, quantification and characterization procedures were developed and applied to representative MMG signals that were recorded from a pregnant woman at regular intervals starting at 37 weeks of gestation until the subject reached active labor.Results: Multiple MMG recordings were successfully performed on the subject before she went into active labor. The extracted MMG burst activity showed a statistically significant correlation (r = 0.2; p < 0.001) with the contractile events perceived by mothers. The time-frequency analysis of the burst activity showed a power shift towards higher-frequency at 48 h before the subject went into active labor as Compared to earlier recordings. Further there was a gradual increase in the synchrony in the higher-frequency band as the subject reached close to active labor.Conclusions: The non-invasive recording of the magnetic signals of pregnant uterus with high spatial-temporal resolution can provide an insight into the preparatory phase of labor and has the potential of predicting term and preterm labor. (c) 2009 Elsevier Ireland Ltd. All rights reserved.