Executive response monitoring and inhibitory control in children with phenylketonuria: effects of expectancy.
Executive response monitoring and inhibitory control in children with phenylketonuria: effects of expectancy.
复制标题
苯丙酮尿症儿童的执行反应监测和抑制控制：预期的影响。
DOI：
10.1080/87565641.2012.718816
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发表时间：
2013
影响因子：
1.5
通讯作者：
White,DesireeA
中科院分区：
文献类型：
--
作者：
Araujo,GabrielC;Christ,ShawnE;Grange,DorothyK;Steiner,RobertD;Coleman,Carla;Timmerman,Evonne;White,DesireeA
在苯丙酮尿症（PKU）儿童和对照组（6-18岁）中，使用Go/No-Go任务检查了反应监测（错误后减慢）和抑制控制（委托错误），其中非目标期望较高（PKUn= 37; controln= 55）与较低（PKUn= 24; controln= 25）。在这两个任务中，PKU儿童表现出受损的监测和抑制控制，但错误后减慢模式是不同的。与对照组相比，具有较高期望值的PKU儿童减慢得更多（监测效率较低），而具有较低期望值的PKU儿童减慢得更少（监测较少）。没有注意到年龄或苯丙氨酸水平的影响。这些结果表明，期望差异影响监测和抑制控制PKU。
Response monitoring (post-error slowing) and inhibitory control (commission errors) were examined in children with phenylketonuria (PKU) and controls (6–18 years) using Go/No-Go tasks with higher (PKUn= 37; controln= 55) versus lower (PKUn= 24; controln= 25) non-target expectancy. On both tasks children with PKU exhibited impaired monitoring and inhibitory control, but the post-error slowing pattern was different. With higher expectancy children with PKU slowed more (less efficient monitoring) and with lower expectancy slowed less (less monitoring) than controls. No effects of age or phenylalanine level were noted. These results indicate that expectancy differentially effects monitoring and inhibitory control in PKU.